Interactor 1: PKNX1 (P55347)
Homeobox protein PKNOX1 (Homeobox protein PREP-1) (PBX/knotted homeobox 1)
Gene: PKNOX1

Interactor 2: PBX4 (Q9BYU1)
Pre-B-cell leukemia transcription factor 4 (Homeobox protein PBX4)
Gene: PBX4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.926

The method score is based on:

Property Details
Experiments 26186194, 28514442, 32296183, 33961781, unassigned1304
Identification Methods affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, validated two hybrid, two hybrid prey pooling approach, two hybrid array
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Homeobox_KN~Homeobox_KN
Common GO terms GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005634 - nucleus
GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 436
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024