HitPredict

Interactor 1: SEC13 (P55735)
Protein SEC13 homolog (GATOR2 complex protein SEC13) (SEC13-like protein 1) (SEC13-related protein)
Gene: SEC13

Interactor 2: WDR5 (P61964)
WD repeat-containing protein 5 (BMP2-induced 3-kb gene protein)
Gene: WDR5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	33022573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	WD40~WD40
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 322 Hs			1 334
+	Hs
		903418 FBXW7_HUMAN (87-316): 1.49e-41: 154: 14.72		WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00
+	Hs
		903349 WDR5B_HUMAN (2-194): 1.22e-31: 122: 16.67		WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00
+	Hs
		903551 NLE1_HUMAN (196-317): 5.64e-28: 114: 20.49		WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00
+	Hs
		903428 SNR40_HUMAN (3-131): 4.97e-25: 104: 22.22		WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00
+	Hs
		792949 LIS1_HUMAN (208-320): 5.26e-24: 102: 20.35		WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00
+	Dm
		1358845 WDS_DROME (90-319): 1.09e-47: 165: 19.57		WDS_DROME (3-290): 7.53e-92: 279: 31.21
+	Mm
		925836 LIS1_MOUSE (208-320): 4.41e-24: 103: 20.35		LIS1_MOUSE (2-289): 1.02e-94: 288: 29.49
+	Hs
		792935 LIS1_HUMAN (208-320): 5.26e-24: 102: 20.35		LIS1_HUMAN (2-289): 1.55e-94: 288: 29.49
+	Hs
		1240442 POC1A_HUMAN (5-132): 1.69e-26: 109: 20.31		POC1B_HUMAN (5-251): 5.05e-84: 263: 27.89
+	Hs
		209467 SNR40_HUMAN (3-131): 4.97e-25: 104: 22.22		PLRG1_HUMAN (2-333): 5.29e-85: 267: 26.05
+	Hs
		1288273 SNR40_HUMAN (3-131): 4.97e-25: 104: 22.22		WDR83_HUMAN (25-333): 8.76e-84: 257: 31.83
+	Sp
		999838 TUP11_SCHPO (2-250): 9.63e-58: 198: 20.93		TUP11_SCHPO (3-117): 1.07e-31: 126: 25.19
+	Sp
		999842 TUP11_SCHPO (2-250): 9.63e-58: 198: 20.93		TUP12_SCHPO (2-118): 1.15e-30: 123: 20.30
+	Hs
		1103007 FBXW7_HUMAN (87-316): 1.49e-41: 154: 14.72		SMU1_HUMAN (30-331): 7.66e-39: 145: 28.71
+	Hs
		1281292 FBXW7_HUMAN (87-316): 1.49e-41: 154: 14.72		FBXW7_HUMAN (198-333): 4.06e-28: 116: 30.15
+	Dm
		1358859 WDS_DROME (90-319): 1.09e-47: 165: 19.57		FBXW7_DROME (40-169): 6.72e-18: 86.7: 39.10
+	Hs
		1346954 NLE1_HUMAN (196-317): 5.64e-28: 114: 20.49		NLE1_HUMAN (197-332): 1.05e-32: 128: 22.54
+	Hs
		1074780 TAF5_HUMAN (171-320): 7.18e-23: 101: 14.61		TAF5_HUMAN (163-330): 6.22e-12: 68.6: 25.25
+	Hs
		197071 SNR40_HUMAN (3-131): 4.97e-25: 104: 22.22		PRP4_HUMAN (244-333): 1.12e-10: 64.2: 19.39