HitPredict

Interactor 1: SEC13 (P55735)
Protein SEC13 homolog (GATOR2 complex protein SEC13) (SEC13-like protein 1) (SEC13-related protein)
Gene: SEC13

Interactor 2: CUL4A (Q13619)
Cullin-4A (CUL-4A)
Gene: CUL4A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30945288
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 322 Hs			1 759
+	Hs
		1043085 WDR5B_HUMAN (2-194): 1.22e-31: 122: 16.67		CUL4A_HUMAN (1-759): 0: 963: 100.00
+	Hs
		1043499 FBXW7_HUMAN (87-316): 1.49e-41: 154: 14.72		CUL4B_HUMAN (10-759): 0: 927: 82.31
+	Hs
		878179 SEC13_HUMAN (1-322): 1.89e-85: 261: 100.00		CUL3_HUMAN (32-759): 0: 814: 38.23
+	Hs
		1043157 SNR40_HUMAN (3-131): 4.97e-25: 104: 22.22		CUL4A_HUMAN (1-759): 0: 963: 100.00
+	Hs
		792982 LIS1_HUMAN (208-320): 5.26e-24: 102: 20.35		CUL4A_HUMAN (1-759): 0: 963: 100.00
+	Hs
		1043114 POC1B_HUMAN (2-95): 2.54e-19: 89.8: 29.79		CUL4A_HUMAN (1-759): 0: 963: 100.00
+	Hs
		1043441 WDR5B_HUMAN (2-194): 1.22e-31: 122: 16.67		CUL4B_HUMAN (10-759): 0: 927: 82.31
+	Hs
		1043509 SNR40_HUMAN (3-131): 4.97e-25: 104: 22.22		CUL4B_HUMAN (10-759): 0: 927: 82.31
+	Hs
		903208 WDR5_HUMAN (249-320): 1.4e-10: 63.3: 16.67		CUL4A_HUMAN (1-759): 0: 963: 100.00
+	Hs
		1043469 POC1B_HUMAN (2-95): 2.54e-19: 89.8: 29.79		CUL4B_HUMAN (10-759): 0: 927: 82.31
+	Hs
		152876 APAF_HUMAN (12-134): 4.76e-11: 65.9: 21.71		CUL4B_HUMAN (10-759): 0: 927: 82.31
+	Hs
		903209 WDR5_HUMAN (249-320): 1.4e-10: 63.3: 16.67		CUL4B_HUMAN (10-759): 0: 927: 82.31
+	Hs
		1042655 NLE1_HUMAN (196-317): 5.64e-28: 114: 20.49		CUL3_HUMAN (32-759): 0: 814: 38.23
+	Hs
		1041647 TAF5_HUMAN (171-320): 7.18e-23: 101: 14.61		CUL3_HUMAN (32-759): 0: 814: 38.23
+	Hs
		1042101 POC1B_HUMAN (2-95): 2.54e-19: 89.8: 29.79		CUL3_HUMAN (32-759): 0: 814: 38.23
+	Mm
		1257398 FBXW7_MOUSE (87-316): 5.76e-42: 156: 14.72		CUL1_MOUSE (59-759): 0: 745: 30.55
+	Hs
		1041133 FBXW7_HUMAN (87-316): 1.49e-41: 154: 14.72		CUL1_HUMAN (59-759): 0: 745: 30.55
+	Hs
		152875 APAF_HUMAN (12-134): 4.76e-11: 65.9: 21.71		CUL3_HUMAN (32-759): 0: 814: 38.23
+	Hs
		903207 WDR5_HUMAN (249-320): 1.4e-10: 63.3: 16.67		CUL3_HUMAN (32-759): 0: 814: 38.23
+	Hs
		903206 WDR5_HUMAN (249-320): 1.4e-10: 63.3: 16.67		CUL1_HUMAN (59-759): 0: 745: 30.55