HitPredict

Interactor 1: SEC13 (P55735)
Protein SEC13 homolog (GATOR2 complex protein SEC13) (SEC13-like protein 1) (SEC13-related protein)
Gene: SEC13

Interactor 2: SAR1A (Q9NR31)
Small COPII coat GTPase SAR1A (EC 3.6.5.2) (COPII-associated small GTPase) (Secretion-associated Ras-related GTPase 1A)
Gene: SAR1A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35271311, 35844135
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006886 - intracellular protein transport GO:0030127 - COPII vesicle coat GO:0090110 - COPII-coated vesicle cargo loading GO:1904262 - negative regulation of TORC1 signaling
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 322 Hs			1 198
+	Hs
		878168 SEC13_HUMAN (1-322): 1.89e-85: 261: 100.00		ARF6_HUMAN (21-196): 4.24e-75: 225: 30.68
+	Hs
		878270 SEC13_HUMAN (1-322): 1.89e-85: 261: 100.00		SAR1B_HUMAN (1-198): 1.74e-58: 183: 89.90
+	Sc
		594426 SEC13_YEAST (4-89): 5.8e-10: 61.3: 25.00		SAR1_YEAST (4-197): 2.97e-75: 226: 59.79
+	Hs
		793048 LIS1_HUMAN (208-320): 5.26e-24: 102: 20.35		SAR1B_HUMAN (1-198): 1.74e-58: 183: 89.90
+	Hs
		903100 WDR5_HUMAN (249-320): 1.4e-10: 63.3: 16.67		RAB1A_HUMAN (15-197): 4.65e-62: 193: 18.62
+	Hs
		903508 WDR5_HUMAN (249-320): 1.4e-10: 63.3: 16.67		RAB1B_HUMAN (18-197): 1.27e-61: 191: 18.92
+	Hs
		900348 WDR5_HUMAN (249-320): 1.4e-10: 63.3: 16.67		RHOA_HUMAN (27-195): 9.13e-59: 184: 20.81