HitPredict

Interactor 1: SEC13 (P55735)
Protein SEC13 homolog (GATOR2 complex protein SEC13) (SEC13-like protein 1) (SEC13-related protein)
Gene: SEC13

Interactor 2: TAB2 (Q9NYJ8)
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 (Mitogen-activated protein kinase kinase kinase 7-interacting protein 2) (TAK1-binding protein 2) (TAB-2) (TGF-beta-activated kinase 1-binding protein 2)
Gene: TAB2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	14743216
Identification Methods	tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005765 - lysosomal membrane GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 322 Hs			1 693
+	Dm
		631315 SEC13_DROME (1-305): 1.44e-72: 230: 57.33		BRM_DROME (165-665): 1e-43: 172: 12.74
+	Dm
		631309 EBI_DROME (206-320): 5.33e-18: 86.4: 24.19		BRM_DROME (165-665): 1e-43: 172: 12.74
+	Hs
		979963 FBXW7_HUMAN (87-316): 1.49e-41: 154: 14.72		IF4G1_HUMAN (71-521): 3.73e-21: 101: 8.28
+	Hs
		847050 FBXW7_HUMAN (87-316): 1.49e-41: 154: 14.72		SMCA4_HUMAN (111-415): 6.46e-09: 61.7: 8.81
+	Hs
		282948 CIAO1_HUMAN (12-93): 1.73e-09: 60: 28.09		PHLB1_HUMAN (44-596): 6.26e-34: 141: 14.08
+	Hs
		847053 SNR40_HUMAN (3-131): 4.97e-25: 104: 22.22		SMCA4_HUMAN (111-415): 6.46e-09: 61.7: 8.81
+	Hs
		903152 WDR5_HUMAN (249-320): 1.4e-10: 63.3: 16.67		IF4G1_HUMAN (71-521): 3.73e-21: 101: 8.28
+	Sp
		142026 SEC13_SCHPO (3-147): 3.98e-14: 73.2: 24.85		SEC31_SCHPO (81-331): 6.3e-09: 61.6: 9.69
+	Hs
		903374 WDR5_HUMAN (249-320): 1.4e-10: 63.3: 16.67		KMT2C_HUMAN (103-538): 1.38e-09: 63.9: 14.25
+	Sc
		758551 SEC13_YEAST (4-89): 5.8e-10: 61.3: 25.00		SEC31_YEAST (37-369): 1.01e-09: 64.3: 11.64