HitPredict

Interactor 1: PAX9 (P55771)
Paired box protein Pax-9
Gene: PAX9

Interactor 2: ZFHX3 (Q15911)
Zinc finger homeobox protein 3 (AT motif-binding factor 1) (AT-binding transcription factor 1) (Alpha-fetoprotein enhancer-binding protein) (Zinc finger homeodomain protein 3) (ZFH-3)
Gene: ZFHX3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 341 Hs			1 3703
+	Hs
		641420 PAX6_HUMAN (1-145): 1.49e-71: 230: 64.14		ZFHX3_HUMAN (1-3703): 0: 1661: 100.00
+	Hs
		620157 PAX7_HUMAN (4-132): 1.95e-65: 216: 72.73		ZFHX3_HUMAN (1-3703): 0: 1661: 100.00
+	Hs
		878430 PAX9_HUMAN (1-341): 0: 535: 100.00		ZFHX4_HUMAN (1-3703): 0: 1316: 47.72
+	Hs
		973860 PAX2_HUMAN (1-191): 1.66e-85: 265: 56.55		ZFHX4_HUMAN (1-3703): 0: 1316: 47.72
+	Hs
		988779 PAX8_HUMAN (1-204): 4.15e-77: 245: 50.95		ZFHX4_HUMAN (1-3703): 0: 1316: 47.72
+	Hs
		641468 PAX6_HUMAN (1-145): 1.49e-71: 230: 64.14		ZFHX4_HUMAN (1-3703): 0: 1316: 47.72
+	Hs
		620171 PAX7_HUMAN (4-132): 1.95e-65: 216: 72.73		ZFHX4_HUMAN (1-3703): 0: 1316: 47.72
+	Hs
		641536 PAX6_HUMAN (1-145): 1.49e-71: 230: 64.14		ZN607_HUMAN (562-1173): 2.12e-43: 173: 12.50
+	Hs
		641526 PAX6_HUMAN (1-145): 1.49e-71: 230: 64.14		ZN521_HUMAN (600-1143): 5.59e-27: 123: 16.75
+	Hs
		641346 PAX6_HUMAN (1-145): 1.49e-71: 230: 64.14		LHX2_HUMAN (2591-2784): 3.55e-17: 89.3: 22.68