HitPredict

Interactor 1: PAX9 (P55771)
Paired box protein Pax-9
Gene: PAX9

Interactor 2: KMT2C (Q8NEZ4)
Histone-lysine N-methyltransferase 2C (Lysine N-methyltransferase 2C) (EC 2.1.1.364) (Homologous to ALR protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 3)
Gene: KMT2C

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 341 Hs			1 4911
+	Hs
		973865 PAX2_HUMAN (1-191): 1.66e-85: 265: 56.55		KMT2C_HUMAN (1-4911): 0: 2416: 100.00
+	Hs
		988783 PAX8_HUMAN (1-204): 4.15e-77: 245: 50.95		KMT2C_HUMAN (1-4911): 0: 2416: 100.00
+	Hs
		641482 PAX6_HUMAN (1-145): 1.49e-71: 230: 64.14		KMT2C_HUMAN (1-4911): 0: 2416: 100.00
+	Hs
		620175 PAX7_HUMAN (4-132): 1.95e-65: 216: 72.73		KMT2C_HUMAN (1-4911): 0: 2416: 100.00
+	Hs
		878447 PAX9_HUMAN (1-341): 0: 535: 100.00		REQU_HUMAN (359-435): 2.72e-12: 74.3: 41.25
+	Hs
		152618 PAX9_HUMAN (1-341): 0: 535: 100.00		KMT2D_HUMAN (2766-3637): 7.14e-09: 65: 8.82
+	Hs
		973877 PAX2_HUMAN (1-191): 1.66e-85: 265: 56.55		NSD3_HUMAN (1-668): 2.87e-64: 246: 13.52
+	Hs
		971651 PAX5_HUMAN (4-220): 3.55e-79: 248: 50.23		KMT2A_HUMAN (159-332): 7.57e-32: 140: 22.16
+	Dm
		112013 L0MPR7_DROME (4-188): 2.9e-66: 219: 49.19		Q9W1H0_DROME (954-1243): 2.58e-36: 155: 22.77
+	Dm
		1359818 Q9V490_DROME (4-188): 1.66e-65: 217: 49.19		Q9W1H0_DROME (954-1243): 2.58e-36: 155: 22.77
+	Hs
		641393 PAX6_HUMAN (1-145): 1.49e-71: 230: 64.14		CHD3_HUMAN (390-526): 1.86e-31: 139: 21.38
+	Hs
		973870 PAX2_HUMAN (1-191): 1.66e-85: 265: 56.55		DPF1_HUMAN (350-435): 3.04e-13: 77: 40.45
+	Hs
		152629 PAX2_HUMAN (1-191): 1.66e-85: 265: 56.55		KMT2D_HUMAN (2766-3637): 7.14e-09: 65: 8.82
+	Hs
		988790 PAX8_HUMAN (1-204): 4.15e-77: 245: 50.95		DPF1_HUMAN (350-435): 3.04e-13: 77: 40.45
+	Hs
		988791 PAX8_HUMAN (1-204): 4.15e-77: 245: 50.95		REQU_HUMAN (359-435): 2.72e-12: 74.3: 41.25
+	Hs
		152634 PAX8_HUMAN (1-204): 4.15e-77: 245: 50.95		KMT2D_HUMAN (2766-3637): 7.14e-09: 65: 8.82
+	Hs
		641503 PAX6_HUMAN (1-145): 1.49e-71: 230: 64.14		DPF1_HUMAN (350-435): 3.04e-13: 77: 40.45
+	Hs
		641504 PAX6_HUMAN (1-145): 1.49e-71: 230: 64.14		REQU_HUMAN (359-435): 2.72e-12: 74.3: 41.25
+	Hs
		152592 PAX6_HUMAN (1-145): 1.49e-71: 230: 64.14		KMT2D_HUMAN (2766-3637): 7.14e-09: 65: 8.82
+	Hs
		152588 PAX7_HUMAN (4-132): 1.95e-65: 216: 72.73		KMT2D_HUMAN (2766-3637): 7.14e-09: 65: 8.82