HitPredict

Interactor 1: HNRH2 (P55795)
Heterogeneous nuclear ribonucleoprotein H2 (hnRNP H2) (FTP-3) (Heterogeneous nuclear ribonucleoprotein H') (hnRNP H') [Cleaved into: Heterogeneous nuclear ribonucleoprotein H2, N-terminally processed]
Gene: HNRNPH2

Interactor 2: ROA0 (Q13151)
Heterogeneous nuclear ribonucleoprotein A0 (hnRNP A0)
Gene: HNRNPA0

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.806

Property	Details
Experiments	22365833, 26496610
Identification Methods	two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1, RRM_1~zf-RNPHF
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 449 Hs			1 305
+	Hs
		516358 PABP1_HUMAN (1-448): 4.82e-81: 264: 12.29		ROA2_HUMAN (2-297): 6.2e-78: 242: 42.42
+	Hs
		609781 HNRH2_HUMAN (1-449): 1.46e-74: 242: 100.00		ROA2_HUMAN (2-297): 6.2e-78: 242: 42.42
+	Hs
		609726 HNRH1_HUMAN (1-449): 2.8e-73: 239: 96.21		ROA2_HUMAN (2-297): 6.2e-78: 242: 42.42
+	Hs
		201661 HNRH2_HUMAN (1-449): 1.46e-74: 242: 100.00		MSI1H_HUMAN (3-304): 4.84e-61: 199: 29.56
+	Hs
		878707 HNRH2_HUMAN (1-449): 1.46e-74: 242: 100.00		MSI2H_HUMAN (5-303): 2.55e-56: 186: 32.11
+	Hs
		516495 PABP4_HUMAN (1-447): 1.01e-81: 266: 13.59		PABP1_HUMAN (5-186): 8.2e-43: 157: 19.57
+	Hs
		516339 PABP1_HUMAN (1-448): 4.82e-81: 264: 12.29		PABP1_HUMAN (5-186): 8.2e-43: 157: 19.57
+	Hs
		516689 PABP3_HUMAN (1-446): 2.6e-77: 254: 12.23		PABP1_HUMAN (5-186): 8.2e-43: 157: 19.57
+	Hs
		453331 PABP4_HUMAN (1-447): 1.01e-81: 266: 13.59		ROA1_HUMAN (85-183): 1.84e-26: 108: 33.33
+	Hs
		453107 PABP1_HUMAN (1-448): 4.82e-81: 264: 12.29		ROA1_HUMAN (85-183): 1.84e-26: 108: 33.33
+	Hs
		516424 PABP1_HUMAN (1-448): 4.82e-81: 264: 12.29		ROA3_HUMAN (89-183): 5.41e-23: 99.3: 34.74
+	Hs
		453239 HNRH2_HUMAN (1-449): 1.46e-74: 242: 100.00		ROA1_HUMAN (85-183): 1.84e-26: 108: 33.33
+	Hs
		453174 HNRH1_HUMAN (1-449): 2.8e-73: 239: 96.21		ROA1_HUMAN (85-183): 1.84e-26: 108: 33.33
+	Hs
		162035 PABP4_HUMAN (1-447): 1.01e-81: 266: 13.59		HNRDL_HUMAN (3-88): 1.69e-15: 78.1: 27.91
+	Hs
		516511 PABP1_HUMAN (1-448): 4.82e-81: 264: 12.29		HNRPD_HUMAN (3-83): 6.84e-16: 78.8: 28.40
+	Hs
		161948 PABP1_HUMAN (1-448): 4.82e-81: 264: 12.29		HNRDL_HUMAN (3-88): 1.69e-15: 78.1: 27.91
+	Hs
		852002 HNRH2_HUMAN (1-449): 1.46e-74: 242: 100.00		ROA3_HUMAN (89-183): 5.41e-23: 99.3: 34.74
+	Hs
		878658 HNRH2_HUMAN (1-449): 1.46e-74: 242: 100.00		HNRPD_HUMAN (3-83): 6.84e-16: 78.8: 28.40
+	Hs
		161970 HNRH1_HUMAN (1-449): 2.8e-73: 239: 96.21		HNRDL_HUMAN (3-88): 1.69e-15: 78.1: 27.91