HitPredict

Interactor 1: HNRH2 (P55795)
Heterogeneous nuclear ribonucleoprotein H2 (hnRNP H2) (FTP-3) (Heterogeneous nuclear ribonucleoprotein H') (hnRNP H') [Cleaved into: Heterogeneous nuclear ribonucleoprotein H2, N-terminally processed]
Gene: HNRNPH2

Interactor 2: G3BP1 (Q13283)
Ras GTPase-activating protein-binding protein 1 (G3BP-1) (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent DNA helicase VIII) (hDH VIII) (GAP SH3 domain-binding protein 1)
Gene: G3BP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	26777405
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1, RRM_1~zf-RNPHF
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005829 - cytosol GO:1990904 - ribonucleoprotein complex
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 449 Hs			1 466
+	Hs
		1030211 PABP4_HUMAN (1-447): 1.01e-81: 266: 13.59		G3BP1_HUMAN (1-466): 1.13e-102: 316: 100.00
+	Hs
		516494 PABP1_HUMAN (1-448): 4.82e-81: 264: 12.29		G3BP1_HUMAN (1-466): 1.13e-102: 316: 100.00
+	Hs
		1031497 PABP4_HUMAN (1-447): 1.01e-81: 266: 13.59		G3BP2_HUMAN (1-463): 4.59e-76: 248: 58.68
+	Hs
		516742 PABP1_HUMAN (1-448): 4.82e-81: 264: 12.29		G3BP2_HUMAN (1-463): 4.59e-76: 248: 58.68
+	Hs
		1030342 RB12B_HUMAN (10-194): 6.44e-19: 91.8: 22.06		G3BP1_HUMAN (1-466): 1.13e-102: 316: 100.00
+	Zm
		22429 A0A1D6I0G1_MAIZE (4-445): 6.92e-45: 167: 10.24		A0A1D6Q2L8_MAIZE (6-437): 3.94e-61: 208: 23.45
+	Hs
		1031413 PABP4_HUMAN (1-447): 1.01e-81: 266: 13.59		CELF1_HUMAN (330-419): 3.54e-12: 70: 14.29
+	Hs
		516621 PABP1_HUMAN (1-448): 4.82e-81: 264: 12.29		CELF1_HUMAN (330-419): 3.54e-12: 70: 14.29
+	Hs
		1018119 GRSF1_HUMAN (268-361): 1.26e-15: 80.7: 23.47		G3BP2_HUMAN (1-463): 4.59e-76: 248: 58.68
+	Hs
		682919 HNRH1_HUMAN (1-449): 2.8e-73: 239: 96.21		CELF1_HUMAN (330-419): 3.54e-12: 70: 14.29
+	Hs
		582556 NUCL_HUMAN (4-404): 6.61e-09: 60.2: 18.16		G3BP2_HUMAN (1-463): 4.59e-76: 248: 58.68
+	Sc
		376881 PABP_YEAST (103-370): 5.77e-34: 135: 13.87		BRE5_YEAST (9-441): 5.6e-45: 166: 15.31
+	Hs
		855159 HNRPF_HUMAN (1-434): 2.49e-60: 204: 71.72		CELF1_HUMAN (330-419): 3.54e-12: 70: 14.29
+	Dm
		597049 PABP_DROME (3-377): 2.02e-35: 140: 11.49		RB27C_DROME (319-464): 1.03e-12: 71.6: 22.15
+	Ce
		1093632 SYM2_CAEEL (258-361): 9.8e-13: 72.1: 22.22		Q20084_CAEEL (201-422): 3.25e-17: 85.8: 9.69
+	Hs
		1272098 ESRP2_HUMAN (109-191): 5.17e-17: 85.6: 38.55		CELF1_HUMAN (330-419): 3.54e-12: 70: 14.29
+	Hs
		1017976 GRSF1_HUMAN (268-361): 1.26e-15: 80.7: 23.47		CELF1_HUMAN (330-419): 3.54e-12: 70: 14.29
+	Hs
		1272113 RBM12_HUMAN (111-215): 5.28e-15: 79.4: 27.52		CELF1_HUMAN (330-419): 3.54e-12: 70: 14.29
+	Dm
		822836 Q9VGH5_DROME (113-184): 3.71e-10: 64: 31.94		RB27C_DROME (319-464): 1.03e-12: 71.6: 22.15