HitPredict

Interactor 1: HNRH2 (P55795)
Heterogeneous nuclear ribonucleoprotein H2 (hnRNP H2) (FTP-3) (Heterogeneous nuclear ribonucleoprotein H') (hnRNP H') [Cleaved into: Heterogeneous nuclear ribonucleoprotein H2, N-terminally processed]
Gene: HNRNPH2

Interactor 2: DYR1A (Q13627)
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.11.23) (EC 2.7.12.1) (Dual specificity YAK1-related kinase) (HP86) (Protein kinase minibrain homolog) (MNBH) (hMNB)
Gene: DYRK1A

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	36950384
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:1990904 - ribonucleoprotein complex
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 449 Hs			1 763
+	Hs
		1031320 PABP4_HUMAN (1-447): 1.01e-81: 266: 13.59		DYR1A_HUMAN (1-763): 0: 613: 100.00
+	Hs
		516508 PABP1_HUMAN (1-448): 4.82e-81: 264: 12.29		DYR1A_HUMAN (1-763): 0: 613: 100.00
+	Hs
		682804 HNRH1_HUMAN (1-449): 2.8e-73: 239: 96.21		DYR1A_HUMAN (1-763): 0: 613: 100.00
+	Hs
		855054 HNRPF_HUMAN (1-434): 2.49e-60: 204: 71.72		DYR1A_HUMAN (1-763): 0: 613: 100.00
+	Hs
		1043938 RB12B_HUMAN (10-194): 6.44e-19: 91.8: 22.06		DYR1A_HUMAN (1-763): 0: 613: 100.00
+	Hs
		682600 HNRH3_HUMAN (10-86): 8.49e-10: 62.2: 33.77		DYR1A_HUMAN (1-763): 0: 613: 100.00
+	Hs
		582281 NUCL_HUMAN (4-404): 6.61e-09: 60.2: 18.16		DYR1A_HUMAN (1-763): 0: 613: 100.00
+	Hs
		516362 PABP1_HUMAN (1-448): 4.82e-81: 264: 12.29		CDK2_HUMAN (156-420): 1.05e-117: 358: 26.85
+	Hs
		625259 HNRPF_HUMAN (1-434): 2.49e-60: 204: 71.72		CDK2_HUMAN (156-420): 1.05e-117: 358: 26.85
+	Sc
		376610 PABP_YEAST (103-370): 5.77e-34: 135: 13.87		YAK1_YEAST (19-586): 3.53e-116: 371: 29.05
+	Hs
		1254140 ESRP2_HUMAN (109-191): 5.17e-17: 85.6: 38.55		MK15_HUMAN (154-597): 1.31e-115: 361: 25.43
+	Zm
		11850 A0A1D6II08_MAIZE (4-114): 1.84e-15: 80.3: 20.72		A0A1D6FHK3_MAIZE (103-525): 7.64e-118: 362: 22.50
+	Hs
		625442 SART3_HUMAN (2-217): 3.71e-16: 83.3: 23.45		CDK2_HUMAN (156-420): 1.05e-117: 358: 26.85
+	Zm
		9779 A0A1D6EZQ5_MAIZE (4-114): 1.73e-12: 71: 20.72		A0A1D6FHK3_MAIZE (103-525): 7.64e-118: 362: 22.50
+	Hs
		414728 NUCL_HUMAN (4-404): 6.61e-09: 60.2: 18.16		CDK1_HUMAN (156-482): 1.29e-121: 368: 26.57