HitPredict

Interactor 1: HNRH2 (P55795)
Heterogeneous nuclear ribonucleoprotein H2 (hnRNP H2) (FTP-3) (Heterogeneous nuclear ribonucleoprotein H') (hnRNP H') [Cleaved into: Heterogeneous nuclear ribonucleoprotein H2, N-terminally processed]
Gene: HNRNPH2

Interactor 2: AURKB (Q96GD4)
Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (ARK-2) (Aurora-related kinase 2) (STK-1) (Serine/threonine-protein kinase 12) (Serine/threonine-protein kinase 5) (Serine/threonine-protein kinase aurora-B)
Gene: AURKB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31586073
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 449 Hs			1 344
+	Rn
		1144336 PABP1_RAT (1-448): 5.59e-81: 264: 12.29		AKT3_RAT (3-343): 9.7e-137: 398: 28.05
+	Hs
		1031427 PABP4_HUMAN (1-447): 1.01e-81: 266: 13.59		AURKB_HUMAN (1-344): 5.7e-136: 391: 100.00
+	Hs
		516639 PABP1_HUMAN (1-448): 4.82e-81: 264: 12.29		AURKB_HUMAN (1-344): 5.7e-136: 391: 100.00
+	Hs
		568649 PABP4_HUMAN (1-447): 1.01e-81: 266: 13.59		KAPCA_HUMAN (36-342): 1.66e-134: 388: 26.18
+	Hs
		516351 PABP1_HUMAN (1-448): 4.82e-81: 264: 12.29		KAPCA_HUMAN (36-342): 1.66e-134: 388: 26.18
+	Hs
		1292216 PABP3_HUMAN (1-446): 2.6e-77: 254: 12.23		AURKB_HUMAN (1-344): 5.7e-136: 391: 100.00
+	Hs
		1119143 PAP1L_HUMAN (1-446): 4e-77: 253: 12.42		AURKB_HUMAN (1-344): 5.7e-136: 391: 100.00
+	Hs
		160465 HNRH2_HUMAN (1-449): 1.46e-74: 242: 100.00		AURKA_HUMAN (1-334): 2.45e-133: 387: 58.89
+	Hs
		855170 HNRPF_HUMAN (1-434): 2.49e-60: 204: 71.72		AURKB_HUMAN (1-344): 5.7e-136: 391: 100.00
+	Hs
		160457 HNRPF_HUMAN (1-434): 2.49e-60: 204: 71.72		AURKA_HUMAN (1-334): 2.45e-133: 387: 58.89
+	Hs
		1221290 RB12B_HUMAN (10-194): 6.44e-19: 91.8: 22.06		AURKB_HUMAN (1-344): 5.7e-136: 391: 100.00
+	Hs
		160652 RB12B_HUMAN (10-194): 6.44e-19: 91.8: 22.06		AURKA_HUMAN (1-334): 2.45e-133: 387: 58.89
+	Dm
		1213421 MSIR6_DROME (104-192): 8.74e-17: 83.3: 17.98		AKT1_DROME (3-343): 2.15e-133: 394: 28.01
+	Hs
		1063265 SART3_HUMAN (2-217): 3.71e-16: 83.3: 23.45		AURKB_HUMAN (1-344): 5.7e-136: 391: 100.00
+	Hs
		160572 SART3_HUMAN (2-217): 3.71e-16: 83.3: 23.45		AURKA_HUMAN (1-334): 2.45e-133: 387: 58.89
+	Hs
		160374 NUCL_HUMAN (4-404): 6.61e-09: 60.2: 18.16		AURKA_HUMAN (1-334): 2.45e-133: 387: 58.89