HitPredict

Interactor 1: HNRH2 (P55795)
Heterogeneous nuclear ribonucleoprotein H2 (hnRNP H2) (FTP-3) (Heterogeneous nuclear ribonucleoprotein H') (hnRNP H') [Cleaved into: Heterogeneous nuclear ribonucleoprotein H2, N-terminally processed]
Gene: HNRNPH2

Interactor 2: MEP50 (Q9BQA1)
Methylosome protein WDR77 (Androgen receptor cofactor p44) (Methylosome protein 50) (MEP-50) (WD repeat-containing protein 77) (p44/Mep50)
Gene: WDR77

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	28977470
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 449 Hs			1 342
+	Hs
		1031444 PABP4_HUMAN (1-447): 1.01e-81: 266: 13.59		MEP50_HUMAN (1-342): 6.74e-81: 251: 100.00
+	Hs
		682958 HNRH1_HUMAN (1-449): 2.8e-73: 239: 96.21		MEP50_HUMAN (1-342): 6.74e-81: 251: 100.00
+	Hs
		855191 HNRPF_HUMAN (1-434): 2.49e-60: 204: 71.72		MEP50_HUMAN (1-342): 6.74e-81: 251: 100.00
+	Hs
		878702 HNRH2_HUMAN (1-449): 1.46e-74: 242: 100.00		FBXW7_HUMAN (3-236): 5.23e-43: 159: 14.29
+	Hs
		855163 HNRPF_HUMAN (1-434): 2.49e-60: 204: 71.72		FBXW7_HUMAN (3-236): 5.23e-43: 159: 14.29
+	Hs
		903196 PABP4_HUMAN (1-447): 1.01e-81: 266: 13.59		WDR5_HUMAN (247-341): 5.14e-19: 88.2: 19.79
+	Hs
		516438 PABP1_HUMAN (1-448): 4.82e-81: 264: 12.29		WDR5_HUMAN (247-341): 5.14e-19: 88.2: 19.79
+	Hs
		878631 HNRH2_HUMAN (1-449): 1.46e-74: 242: 100.00		WDR5_HUMAN (247-341): 5.14e-19: 88.2: 19.79
+	Hs
		682755 HNRH1_HUMAN (1-449): 2.8e-73: 239: 96.21		WDR5_HUMAN (247-341): 5.14e-19: 88.2: 19.79
+	Hs
		682660 HNRH3_HUMAN (10-86): 8.49e-10: 62.2: 33.77		MEP50_HUMAN (1-342): 6.74e-81: 251: 100.00
+	Hs
		582462 NUCL_HUMAN (4-404): 6.61e-09: 60.2: 18.16		MEP50_HUMAN (1-342): 6.74e-81: 251: 100.00
+	Hs
		855007 HNRPF_HUMAN (1-434): 2.49e-60: 204: 71.72		WDR5_HUMAN (247-341): 5.14e-19: 88.2: 19.79
+	Hs
		582421 NUCL_HUMAN (4-404): 6.61e-09: 60.2: 18.16		FBXW7_HUMAN (3-236): 5.23e-43: 159: 14.29
+	Hs
		903236 SART3_HUMAN (2-217): 3.71e-16: 83.3: 23.45		WDR5_HUMAN (247-341): 5.14e-19: 88.2: 19.79
+	Hs
		582176 NUCL_HUMAN (4-404): 6.61e-09: 60.2: 18.16		WDR5_HUMAN (247-341): 5.14e-19: 88.2: 19.79
+	Hs
		197022 SART3_HUMAN (2-217): 3.71e-16: 83.3: 23.45		PRP4_HUMAN (253-341): 3.86e-10: 62.8: 13.40