HitPredict

Interactor 1: HNRH2 (P55795)
Heterogeneous nuclear ribonucleoprotein H2 (hnRNP H2) (FTP-3) (Heterogeneous nuclear ribonucleoprotein H') (hnRNP H') [Cleaved into: Heterogeneous nuclear ribonucleoprotein H2, N-terminally processed]
Gene: HNRNPH2

Interactor 2: AGO1 (Q9UL18)
Protein argonaute-1 (Argonaute1) (hAgo1) (Argonaute RISC catalytic component 1) (Eukaryotic translation initiation factor 2C 1) (eIF-2C 1) (eIF2C 1) (Putative RNA-binding protein Q99)
Gene: AGO1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	17932509
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 449 Hs			1 857
+	Hs
		516737 PABP1_HUMAN (1-448): 4.82e-81: 264: 12.29		AGO1_HUMAN (1-857): 0: 1222: 100.00
+	Mm
		665763 PABP1_MOUSE (1-448): 8.44e-81: 264: 12.29		AGO2_MOUSE (3-857): 0: 1213: 82.36
+	Mm
		1208650 Q99LF8_MOUSE (1-447): 2.76e-80: 263: 13.59		AGO2_MOUSE (3-857): 0: 1213: 82.36
+	Hs
		1329989 PABP3_HUMAN (1-446): 2.6e-77: 254: 12.23		AGO1_HUMAN (1-857): 0: 1222: 100.00
+	Hs
		516735 PABP1_HUMAN (1-448): 4.82e-81: 264: 12.29		AGO2_HUMAN (19-857): 0: 1206: 83.43
+	Hs
		516695 PABP1_HUMAN (1-448): 4.82e-81: 264: 12.29		AGO3_HUMAN (1-857): 0: 1189: 83.83
+	Hs
		1031470 PABP4_HUMAN (1-447): 1.01e-81: 266: 13.59		AGO4_HUMAN (9-857): 0: 1167: 83.04
+	Hs
		516701 PABP1_HUMAN (1-448): 4.82e-81: 264: 12.29		AGO4_HUMAN (9-857): 0: 1167: 83.04
+	Hs
		855252 HNRPF_HUMAN (1-434): 2.49e-60: 204: 71.72		AGO1_HUMAN (1-857): 0: 1222: 100.00
+	Hs
		855251 HNRPF_HUMAN (1-434): 2.49e-60: 204: 71.72		AGO2_HUMAN (19-857): 0: 1206: 83.43
+	Hs
		1063307 SART3_HUMAN (2-217): 3.71e-16: 83.3: 23.45		AGO1_HUMAN (1-857): 0: 1222: 100.00
+	Hs
		1063306 SART3_HUMAN (2-217): 3.71e-16: 83.3: 23.45		AGO2_HUMAN (19-857): 0: 1206: 83.43
+	Hs
		582551 NUCL_HUMAN (4-404): 6.61e-09: 60.2: 18.16		AGO1_HUMAN (1-857): 0: 1222: 100.00
+	Hs
		1063288 SART3_HUMAN (2-217): 3.71e-16: 83.3: 23.45		AGO4_HUMAN (9-857): 0: 1167: 83.04
+	Zm
		9778 A0A1D6EZQ5_MAIZE (4-114): 1.73e-12: 71: 20.72		A0A1D6FB88_MAIZE (9-856): 0: 874: 28.98
+	Dm
		284331 PABP_DROME (3-377): 2.02e-35: 140: 11.49		AUB_DROME (2-815): 0: 596: 21.60