Interactor 1: SUMO3 (P55854)
Small ubiquitin-related modifier 3 (SUMO-3) (SMT3 homolog 1) (SUMO-2) (Ubiquitin-like protein SMT3A) (Smt3A)
Gene: SUMO3

Interactor 2: SENP2 (Q9HC62)
Sentrin-specific protease 2 (EC 3.4.22.-) (Axam2) (SMT3-specific isopeptidase 2) (Smt3ip2) (Sentrin/SUMO-specific protease SENP2)
Gene: SENP2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 1.00 0.938

The method score is based on:

Property Details
Experiments 25416956, 33961781, 12192048, 25944111, 17099700
Identification Methods two hybrid, affinity chromatography technology, enzymatic study, x-ray crystallography, two hybrid prey pooling approach, two hybrid array, anti tag coimmunoprecipitation, validated two hybrid
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Peptidase_C48~Rad60-SLD
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0016925 - protein sumoylation
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 103
Hs

1 589
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Last updated: 15 Jul 2024