Interactor 1: MCM2 (P55861)
DNA replication licensing factor mcm2 (EC 3.6.4.12) (BM28-homolog) (Minichromosome maintenance protein 2) (xMCM2) (p112)
Gene: MCM2

Interactor 2: MCM4A (Q5XK83)
DNA replication licensing factor mcm4-A (EC 3.6.4.12) (CDC21 homolog-A) (Minichromosome maintenance protein 4-A) (xMCM4-A) (P1-CDC21-A) (p98)
Gene: mcm4-a

Species: Xenopus laevis

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 15448142
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains MCM~MCM, MCM~MCM_lid, MCM~MCM_N, MCM~MCM_OB, MCM_N~MCM_N, MCM_N~MCM_OB, MCM_OB~MCM_OB
Common GO terms GO:0000727 - double-strand break repair via break-induced replication
GO:0000785 - chromatin
GO:0003697 - single-stranded DNA binding
GO:0005524 - ATP binding
GO:0006268 - DNA unwinding involved in DNA replication
and 7 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 886
Xl

1 858
+ Hs
+ Dm
+ Xl
+ Hs
+ Xl
+ Hs
+ Hs
+ Xl
+ Hs
+ Hs
+ Dm
+ Dm
+ Sp
+ Sc
+ At
+ Sp
+ Sc
+ Sc
+ Sp
+ Sc

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Last updated: 15 Jul 2024