HitPredict

Interactor 1: EIF3B (P55884)
Eukaryotic translation initiation factor 3 subunit B (eIF3b) (Eukaryotic translation initiation factor 3 subunit 9) (Prt1 homolog) (hPrt1) (eIF-3-eta) (eIF3 p110) (eIF3 p116)
Gene: EIF3B

Interactor 2: RS6 (P62753)
Small ribosomal subunit protein eS6 (40S ribosomal protein S6) (Phosphoprotein NP33)
Gene: RPS6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	27022092, 16286006, 35271311
Identification Methods	affinity chromatography technology, cosedimentation through density gradient, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005829 - cytosol
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 814 Hs			1 249
+	Mm
		917016 EIF3B_MOUSE (1-814): 0: 764: 90.69		RS6_MOUSE (1-249): 9.61e-112: 322: 100.00
+	Sc
		410057 EIF3B_YEAST (139-790): 1.9e-118: 377: 29.36		RS6A_YEAST (1-239): 1.54e-97: 286: 62.76
+	Sc
		480218 EIF2A_YEAST (343-705): 1.57e-86: 289: 19.95		RS6A_YEAST (1-239): 1.54e-97: 286: 62.76
+	Hs
		792960 LIS1_HUMAN (231-410): 5.42e-23: 104: 10.73		RS6_HUMAN (1-249): 9.61e-112: 322: 100.00