HitPredict

Interactor 1: EIF3B (P55884)
Eukaryotic translation initiation factor 3 subunit B (eIF3b) (Eukaryotic translation initiation factor 3 subunit 9) (Prt1 homolog) (hPrt1) (eIF-3-eta) (eIF3 p110) (eIF3 p116)
Gene: EIF3B

Interactor 2: TADBP (Q13148)
TAR DNA-binding protein 43 (TDP-43)
Gene: TARDBP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	20020773
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0010494 - cytoplasmic stress granule
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 814 Hs			1 414
+	Hs
		879239 EIF3B_HUMAN (1-814): 0: 830: 100.00		PABP4_HUMAN (98-274): 3.77e-37: 144: 19.02
+	Hs
		516430 EIF3B_HUMAN (1-814): 0: 830: 100.00		PABP1_HUMAN (2-382): 7.78e-31: 126: 15.95
+	Sc
		376575 EIF3B_YEAST (139-790): 1.9e-118: 377: 29.36		PABP_YEAST (86-269): 2.74e-34: 136: 21.88
+	Sc
		376867 EIF2A_YEAST (343-705): 1.57e-86: 289: 19.95		PABP_YEAST (86-269): 2.74e-34: 136: 21.88
+	Hs
		903188 WDR5_HUMAN (554-729): 7.19e-35: 137: 12.71		TADBP_HUMAN (1-414): 4.24e-84: 264: 100.00
+	Hs
		162000 WDR5_HUMAN (554-729): 7.19e-35: 137: 12.71		HNRDL_HUMAN (62-376): 5.62e-71: 231: 23.60
+	Hs
		852006 WDR5_HUMAN (554-729): 7.19e-35: 137: 12.71		ROA3_HUMAN (98-269): 2.33e-69: 225: 28.57
+	Hs
		903196 WDR5_HUMAN (554-729): 7.19e-35: 137: 12.71		PABP4_HUMAN (98-274): 3.77e-37: 144: 19.02
+	Hs
		516438 WDR5_HUMAN (554-729): 7.19e-35: 137: 12.71		PABP1_HUMAN (2-382): 7.78e-31: 126: 15.95
+	Hs
		903216 WDR5_HUMAN (554-729): 7.19e-35: 137: 12.71		HNRPD_HUMAN (81-238): 5.59e-21: 95.1: 35.93