HitPredict

Interactor 1: EIF3B (P55884)
Eukaryotic translation initiation factor 3 subunit B (eIF3b) (Eukaryotic translation initiation factor 3 subunit 9) (Prt1 homolog) (hPrt1) (eIF-3-eta) (eIF3 p110) (eIF3 p116)
Gene: EIF3B

Interactor 2: CIC (Q96RK0)
Protein capicua homolog
Gene: CIC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	29844126
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 814 Hs			1 2517
+	Hs
		903450 WDR5_HUMAN (554-729): 7.19e-35: 137: 12.71		CIC_HUMAN (1-2517): 0: 961: 100.00
+	Hs
		1074805 TAF5_HUMAN (304-497): 3.2e-13: 75.6: 18.32		CIC_HUMAN (1-2517): 0: 961: 100.00
+	Hs
		879366 EIF3B_HUMAN (1-814): 0: 830: 100.00		SRRM2_HUMAN (291-1369): 4.76e-10: 67.9: 8.34
+	Hs
		245575 TBL1X_HUMAN (408-730): 4.48e-54: 198: 11.02		SOX2_HUMAN (1073-1308): 2.83e-57: 204: 24.05
+	Hs
		818441 TBL1R_HUMAN (408-730): 1.7e-53: 195: 11.90		SOX2_HUMAN (1073-1308): 2.83e-57: 204: 24.05
+	Mm
		1142008 TBL1R_MOUSE (408-730): 9.23e-54: 196: 11.62		Q60I23_MOUSE (1102-1308): 2.84e-56: 201: 27.40
+	Hs
		245570 TBL1X_HUMAN (408-730): 4.48e-54: 198: 11.02		SOX6_HUMAN (887-1289): 5.1e-35: 148: 16.28
+	Hs
		817868 WDR5_HUMAN (554-729): 7.19e-35: 137: 12.71		SOX2_HUMAN (1073-1308): 2.83e-57: 204: 24.05
+	Hs
		245569 TBL1X_HUMAN (408-730): 4.48e-54: 198: 11.02		SOX5_HUMAN (833-1211): 2.27e-29: 129: 17.71
+	Hs
		903155 WDR5_HUMAN (554-729): 7.19e-35: 137: 12.71		SRY_HUMAN (1065-1189): 2.77e-37: 142: 25.60
+	Hs
		245652 TBL1X_HUMAN (408-730): 4.48e-54: 198: 11.02		NCOR2_HUMAN (290-1816): 8.11e-14: 80.2: 8.06
+	Hs
		1302927 NLE1_HUMAN (507-723): 2.49e-34: 139: 17.03		MINT_HUMAN (730-2515): 3e-28: 127: 9.45
+	Hs
		1346974 NLE1_HUMAN (507-723): 2.49e-34: 139: 17.03		NCOR2_HUMAN (290-1816): 8.11e-14: 80.2: 8.06
+	Hs
		1346970 NLE1_HUMAN (507-723): 2.49e-34: 139: 17.03		SRRM2_HUMAN (291-1369): 4.76e-10: 67.9: 8.34
+	Hs
		903374 WDR5_HUMAN (554-729): 7.19e-35: 137: 12.71		KMT2C_HUMAN (1873-2516): 1.5e-09: 66.4: 10.57
+	Mm
		903669 WDR5_MOUSE (554-729): 7.19e-35: 137: 12.71		KMT2C_MOUSE (641-2516): 2.93e-09: 65.3: 9.74
+	Hs
		1309170 TBL1Y_HUMAN (506-729): 1.02e-27: 120: 12.82		NCOR2_HUMAN (290-1816): 8.11e-14: 80.2: 8.06
+	Hs
		989530 TAF5_HUMAN (304-497): 3.2e-13: 75.6: 18.32		SOX4_HUMAN (1091-1186): 2.77e-25: 114: 31.25
+	Hs
		267755 TAF5L_HUMAN (343-501): 2.2e-12: 72.5: 19.63		SOX4_HUMAN (1091-1186): 2.77e-25: 114: 31.25
+	Hs
		793042 LIS1_HUMAN (231-410): 5.42e-23: 104: 10.73		SRRM2_HUMAN (291-1369): 4.76e-10: 67.9: 8.34