HitPredict

Interactor 1: EIF3B (P55884)
Eukaryotic translation initiation factor 3 subunit B (eIF3b) (Eukaryotic translation initiation factor 3 subunit 9) (Prt1 homolog) (hPrt1) (eIF-3-eta) (eIF3 p110) (eIF3 p116)
Gene: EIF3B

Interactor 2: HDAC5 (Q9UQL6)
Histone deacetylase 5 (HD5) (EC 3.5.1.98) (Antigen NY-CO-9)
Gene: HDAC5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21081666
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 814 Hs			1 1122
+	Hs
		879186 EIF3B_HUMAN (1-814): 0: 830: 100.00		HDAC4_HUMAN (1-1101): 0: 653: 54.96
+	Hs
		879312 EIF3B_HUMAN (1-814): 0: 830: 100.00		HDAC2_HUMAN (680-1113): 1.34e-153: 468: 21.68
+	Hs
		245649 TBL1X_HUMAN (408-730): 4.48e-54: 198: 11.02		HDAC5_HUMAN (1-1122): 0: 727: 100.00
+	Hs
		1318188 TBL1R_HUMAN (408-730): 1.7e-53: 195: 11.90		HDAC5_HUMAN (1-1122): 0: 727: 100.00
+	Hs
		903610 WDR5_HUMAN (554-729): 7.19e-35: 137: 12.71		HDAC5_HUMAN (1-1122): 0: 727: 100.00
+	Hs
		245584 TBL1X_HUMAN (408-730): 4.48e-54: 198: 11.02		HDAC4_HUMAN (1-1101): 0: 653: 54.96
+	Hs
		880817 TBL1R_HUMAN (408-730): 1.7e-53: 195: 11.90		HDAC4_HUMAN (1-1101): 0: 653: 54.96
+	Hs
		245622 TBL1X_HUMAN (408-730): 4.48e-54: 198: 11.02		HDAC7_HUMAN (121-1122): 4.12e-159: 499: 40.82
+	Hs
		1260185 TBL1R_HUMAN (408-730): 1.7e-53: 195: 11.90		HDAC7_HUMAN (121-1122): 4.12e-159: 499: 40.82
+	Hs
		245600 TBL1X_HUMAN (408-730): 4.48e-54: 198: 11.02		HDAC1_HUMAN (673-1103): 1.54e-153: 468: 21.16
+	Hs
		245623 TBL1X_HUMAN (408-730): 4.48e-54: 198: 11.02		HDAC2_HUMAN (680-1113): 1.34e-153: 468: 21.68
+	Hs
		1038686 TBL1R_HUMAN (408-730): 1.7e-53: 195: 11.90		HDAC1_HUMAN (673-1103): 1.54e-153: 468: 21.16
+	Hs
		1270423 TBL1R_HUMAN (408-730): 1.7e-53: 195: 11.90		HDAC2_HUMAN (680-1113): 1.34e-153: 468: 21.68
+	Hs
		177148 TBL1X_HUMAN (408-730): 4.48e-54: 198: 11.02		HDAC3_HUMAN (679-1119): 5.97e-144: 441: 21.57
+	Hs
		177377 TBL1R_HUMAN (408-730): 1.7e-53: 195: 11.90		HDAC3_HUMAN (679-1119): 5.97e-144: 441: 21.57
+	Hs
		903202 WDR5_HUMAN (554-729): 7.19e-35: 137: 12.71		HDAC1_HUMAN (673-1103): 1.54e-153: 468: 21.16
+	Hs
		903404 WDR5_HUMAN (554-729): 7.19e-35: 137: 12.71		HDAC2_HUMAN (680-1113): 1.34e-153: 468: 21.68
+	Hs
		177249 WDR5_HUMAN (554-729): 7.19e-35: 137: 12.71		HDAC3_HUMAN (679-1119): 5.97e-144: 441: 21.57
+	Hs
		177369 TBL1Y_HUMAN (506-729): 1.02e-27: 120: 12.82		HDAC3_HUMAN (679-1119): 5.97e-144: 441: 21.57
+	Dm
		1182201 EBI_DROME (272-524): 6.98e-22: 103: 12.78		Q7KTS4_DROME (681-1119): 6.09e-143: 439: 22.08