HitPredict

Interactor 1: FCGRN (P55899)
IgG receptor FcRn large subunit p51 (FcRn) (IgG Fc fragment receptor transporter alpha chain) (Neonatal Fc receptor)
Gene: FCGRT

Interactor 2: PTPRS (Q13332)
Receptor-type tyrosine-protein phosphatase S (R-PTP-S) (EC 3.1.3.48) (Receptor-type tyrosine-protein phosphatase sigma) (R-PTP-sigma)
Gene: PTPRS

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.80	0.726

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	C1-set~fn3, C1-set~Ig_3
Common GO terms	-
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 365 Hs			1 1948
+	Hs
		489926 FCGRN_HUMAN (1-365): 7.52e-116: 342: 100.00		PTPRF_HUMAN (1-1948): 0: 1528: 65.42
+	Hs
		441172 HLAG_HUMAN (1-307): 6.38e-133: 384: 27.36		PTPRC_HUMAN (450-1662): 1.43e-85: 311: 15.29
+	Hs
		570359 HLAG_HUMAN (1-307): 6.38e-133: 384: 27.36		PTPRU_HUMAN (211-781): 3.44e-19: 97.4: 14.71
+	Hs
		1103651 HFE_HUMAN (29-307): 3.48e-30: 120: 28.22		PTPRU_HUMAN (211-781): 3.44e-19: 97.4: 14.71
+	Hs
		1069920 HFE_HUMAN (29-307): 3.48e-30: 120: 28.22		PTPRK_HUMAN (113-670): 1.42e-10: 68.9: 15.72