Interactor 1: BID (P55957)
BH3-interacting domain death agonist (p22 BID) (BID) [Cleaved into: BH3-interacting domain death agonist p15 (p15 BID); BH3-interacting domain death agonist p13 (p13 BID); BH3-interacting domain death agonist p11 (p11 BID)]
Gene: BID

Interactor 2: FADD (Q13158)
FAS-associated death domain protein (FAS-associating death domain-containing protein) (Growth-inhibiting gene 3 protein) (Mediator of receptor induced toxicity)
Gene: FADD

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.33 0.60 0.445

The method score is based on:

Property Details
Experiments 15659383
Identification Methods biochemical
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005123 - death receptor binding
GO:0005829 - cytosol
GO:0008625 - extrinsic apoptotic signaling pathway via death domain receptors
GO:0043065 - positive regulation of apoptotic process
GO:2001238 - positive regulation of extrinsic apoptotic signaling pathway
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 195
Hs

1 208
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024