HitPredict

Interactor 1: D3DMF6 (D3DMF6)
Mitogen-activated protein kinase kinase kinase (EC 2.7.11.25)
Gene: wnd

Interactor 2: RHO1 (P48148)
Ras-like GTP-binding protein Rho1
Gene: RHO1

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25961917
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 950 Dm			1 192
+	Hs
		199540 M3K13_HUMAN (9-910): 1.4e-131: 422: 34.61		CDC42_HUMAN (1-192): 6.45e-76: 227: 53.89
+	Hs
		647868 MARK3_HUMAN (86-756): 6.63e-126: 400: 17.61		RAC1_HUMAN (1-192): 1.19e-80: 239: 57.73
+	Hs
		925606 TAOK3_HUMAN (112-911): 3.07e-123: 398: 14.93		RAC1_HUMAN (1-192): 1.19e-80: 239: 57.73
+	Hs
		647858 MARK3_HUMAN (86-756): 6.63e-126: 400: 17.61		RHOA_HUMAN (1-192): 2.63e-78: 233: 86.53
+	Hs
		647872 MARK3_HUMAN (86-756): 6.63e-126: 400: 17.61		RHOG_HUMAN (1-192): 6.73e-78: 232: 55.21
+	Hs
		545213 MARK3_HUMAN (86-756): 6.63e-126: 400: 17.61		RAC2_HUMAN (1-192): 3.29e-77: 230: 55.16
+	Hs
		951328 TAOK3_HUMAN (112-911): 3.07e-123: 398: 14.93		RHOG_HUMAN (1-192): 6.73e-78: 232: 55.21
+	Hs
		545609 TAOK3_HUMAN (112-911): 3.07e-123: 398: 14.93		RAC2_HUMAN (1-192): 3.29e-77: 230: 55.16
+	Hs
		436165 MARK3_HUMAN (86-756): 6.63e-126: 400: 17.61		RHOC_HUMAN (1-192): 5.91e-76: 227: 85.49
+	Hs
		647856 MARK3_HUMAN (86-756): 6.63e-126: 400: 17.61		CDC42_HUMAN (1-192): 6.45e-76: 227: 53.89
+	Hs
		681775 AKT1_HUMAN (16-439): 7.01e-125: 388: 19.28		RAC1_HUMAN (1-192): 1.19e-80: 239: 57.73
+	Hs
		647855 MARK3_HUMAN (86-756): 6.63e-126: 400: 17.61		RAC3_HUMAN (1-179): 7e-75: 225: 57.54
+	Hs
		894416 TAOK3_HUMAN (112-911): 3.07e-123: 398: 14.93		CDC42_HUMAN (1-192): 6.45e-76: 227: 53.89
+	Hs
		647867 MARK3_HUMAN (86-756): 6.63e-126: 400: 17.61		RHOB_HUMAN (1-190): 2.72e-74: 223: 82.11
+	Hs
		892589 TAOK3_HUMAN (112-911): 3.07e-123: 398: 14.93		RAC3_HUMAN (1-179): 7e-75: 225: 57.54
+	Hs
		915967 TAOK3_HUMAN (112-911): 3.07e-123: 398: 14.93		RHOB_HUMAN (1-190): 2.72e-74: 223: 82.11
+	Hs
		545461 MARK2_HUMAN (79-790): 3.43e-120: 387: 15.56		RAC2_HUMAN (1-192): 3.29e-77: 230: 55.16
+	Hs
		436371 MARK2_HUMAN (79-790): 3.43e-120: 387: 15.56		RHOC_HUMAN (1-192): 5.91e-76: 227: 85.49
+	Hs
		894157 MARK2_HUMAN (79-790): 3.43e-120: 387: 15.56		CDC42_HUMAN (1-192): 6.45e-76: 227: 53.89
+	Hs
		892447 MARK2_HUMAN (79-790): 3.43e-120: 387: 15.56		RAC3_HUMAN (1-179): 7e-75: 225: 57.54