Interactor 1: GFRA1 (P56159)
GDNF family receptor alpha-1 (GDNF receptor alpha-1) (GDNFR-alpha-1) (GFR-alpha-1) (RET ligand 1) (TGF-beta-related neurotrophic factor receptor 1)
Gene: GFRA1

Interactor 2: NRTN (Q99748)
Neurturin
Gene: NRTN

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.778

The method score is based on:

Property Details
Experiments 9407096, 10829012
Identification Methods pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains GDNF~TGF_beta
Common GO terms GO:0005102 - signaling receptor binding
GO:0007399 - nervous system development
GO:0030424 - axon
GO:0031175 - neuron projection development
GO:0035860 - glial cell-derived neurotrophic factor receptor signaling pathway
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 465
Hs

1 197
+ Hs
+ Rn
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs

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Last updated: 15 Jul 2024