Interactor 1: SYMC (P56192)
Methionine--tRNA ligase, cytoplasmic (EC 6.1.1.10) (Methionyl-tRNA synthetase) (MetRS)
Gene: MARS1

Interactor 2: AIMP1 (Q12904)
Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (Multisynthase complex auxiliary component p43) [Cleaved into: Endothelial monocyte-activating polypeptide 2 (EMAP-2) (Endothelial monocyte-activating polypeptide II) (EMAP-II) (Small inducible cytokine subfamily E member 1)]
Gene: AIMP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 0.60 0.628

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000049 - tRNA binding
GO:0005829 - cytosol
GO:0016020 - membrane
GO:0017101 - aminoacyl-tRNA synthetase multienzyme complex
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 900
Hs

1 312
+ Dm
+ Sp
+ Sc
+ Ec
+ Sc
+ Hs
+ Ce
+ Ce
+ Dm
+ Sc
+ Tk

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024