HitPredict

Interactor 1: ITA1 (P56199)
Integrin alpha-1 (CD49 antigen-like family member A) (Laminin and collagen receptor) (VLA-1) (CD antigen CD49a)
Gene: ITGA1

Interactor 2: RAC1 (P63000)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (Cell migration-inducing gene 5 protein) (Ras-like protein TC25) (p21-Rac1)
Gene: RAC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0005925 - focal adhesion GO:0007160 - cell-matrix adhesion GO:0016020 - membrane GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1179 Hs			1 192
+	Hs
		564464 ITA1_HUMAN (1-1179): 0: 1320: 100.00		RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67
+	Hs
		545290 ITA1_HUMAN (1-1179): 0: 1320: 100.00		RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19
+	Hs
		880220 ITA1_HUMAN (1-1179): 0: 1320: 100.00		RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64
+	Hs
		880207 ITA1_HUMAN (1-1179): 0: 1320: 100.00		RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19
+	Hs
		880212 ITA1_HUMAN (1-1179): 0: 1320: 100.00		RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35
+	Hs
		880208 ITA1_HUMAN (1-1179): 0: 1320: 100.00		CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31
+	Hs
		880209 ITA1_HUMAN (1-1179): 0: 1320: 100.00		RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98
+	Hs
		436228 ITA1_HUMAN (1-1179): 0: 1320: 100.00		RHOC_HUMAN (5-192): 8.68e-75: 224: 57.45
+	Hs
		566873 ITA2_HUMAN (21-1178): 0: 1066: 39.14		RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00
+	Hs
		564407 ITA2_HUMAN (21-1178): 0: 1066: 39.14		RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67
+	Hs
		566865 ITA2_HUMAN (21-1178): 0: 1066: 39.14		RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19
+	Hs
		566875 ITA2_HUMAN (21-1178): 0: 1066: 39.14		RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35
+	Hs
		566867 ITA2_HUMAN (21-1178): 0: 1066: 39.14		RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98
+	Hs
		613239 ITA6_HUMAN (8-512): 2.18e-67: 250: 17.57		RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00
+	Hs
		564413 ITA6_HUMAN (8-512): 2.18e-67: 250: 17.57		RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67
+	Hs
		545210 ITA6_HUMAN (8-512): 2.18e-67: 250: 17.57		RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19
+	Hs
		613231 ITA6_HUMAN (8-512): 2.18e-67: 250: 17.57		RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19
+	Hs
		613232 ITA6_HUMAN (8-512): 2.18e-67: 250: 17.57		CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31
+	Hs
		613234 ITA6_HUMAN (8-512): 2.18e-67: 250: 17.57		RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98
+	Hs
		436159 ITA6_HUMAN (8-512): 2.18e-67: 250: 17.57		RHOC_HUMAN (5-192): 8.68e-75: 224: 57.45