HitPredict

Interactor 1: D3DU92 (D3DU92)
RNA-binding protein with serine-rich domain 1
Gene: rnps1

Interactor 2: CLK2 (P49760)
Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)
Gene: CLK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	25416956
Identification Methods	two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	GO:0005654 - nucleoplasm GO:0016607 - nuclear speck
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 305 Hs			1 499
+	Hs
		833884 RNPS1_HUMAN (1-234): 2e-34: 128: 100.00		CLK2_HUMAN (1-499): 1.97e-147: 432: 100.00
+	Hs
		834048 RNPS1_HUMAN (1-234): 2e-34: 128: 100.00		CLK3_HUMAN (1-499): 1.7e-136: 409: 59.32
+	Hs
		625442 SART3_HUMAN (2-302): 1.67e-38: 146: 16.32		CDK2_HUMAN (160-488): 4.25e-133: 389: 24.70
+	Hs
		516416 PABP1_HUMAN (65-252): 1.33e-21: 96.9: 16.32		CLK2_HUMAN (1-499): 1.97e-147: 432: 100.00
+	Hs
		516417 PABP1_HUMAN (65-252): 1.33e-21: 96.9: 16.32		CLK3_HUMAN (1-499): 1.7e-136: 409: 59.32
+	Hs
		834033 PABP4_HUMAN (153-248): 4.98e-19: 89.2: 27.08		CLK3_HUMAN (1-499): 1.7e-136: 409: 59.32
+	Hs
		516362 PABP1_HUMAN (65-252): 1.33e-21: 96.9: 16.32		CDK2_HUMAN (160-488): 4.25e-133: 389: 24.70
+	Hs
		853953 NCBP2_HUMAN (128-271): 1.08e-30: 114: 18.06		DYRK2_HUMAN (9-499): 1.04e-115: 355: 22.20
+	Hs
		414928 RNPS1_HUMAN (1-234): 2e-34: 128: 100.00		CDK1_HUMAN (160-485): 3.05e-114: 340: 23.95
+	Hs
		1043810 RNPS1_HUMAN (1-234): 2e-34: 128: 100.00		DYR1A_HUMAN (108-485): 6.52e-105: 331: 28.50
+	Hs
		853885 NCBP2_HUMAN (128-271): 1.08e-30: 114: 18.06		DYR1A_HUMAN (108-485): 6.52e-105: 331: 28.50
+	Hs
		516508 PABP1_HUMAN (65-252): 1.33e-21: 96.9: 16.32		DYR1A_HUMAN (108-485): 6.52e-105: 331: 28.50
+	Hs
		1031320 PABP4_HUMAN (153-248): 4.98e-19: 89.2: 27.08		DYR1A_HUMAN (108-485): 6.52e-105: 331: 28.50
+	At
		621700 RB45A_ARATH (102-252): 2.53e-10: 62.6: 13.07		CDKA1_ARATH (160-486): 4.5e-118: 350: 23.65
+	Sc
		688523 HRB1_YEAST (134-240): 1.35e-09: 60.7: 13.08		KNS1_YEAST (146-418): 3.57e-66: 228: 39.45