Interactor 1: DPOE2 (P56282)
DNA polymerase epsilon subunit 2 (DNA polymerase II subunit 2) (DNA polymerase epsilon subunit B)
Gene: POLE2
Interactor 2: DPOE1 (Q07864)
DNA polymerase epsilon catalytic subunit A (EC 2.7.7.7) (3'-5' exodeoxyribonuclease) (EC 3.1.11.-) (DNA polymerase II subunit A)
Gene: POLE
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.93 | 1.00 | 0.966 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 32296183, 33961781, 21705323, 26186194, 28514442, 27235625, unassigned1304, 10801849 |
| Identification Methods | two hybrid, affinity chromatography technology, pull down, anti tag coimmunoprecipitation, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti bait coimmunoprecipitation |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | DNA_pol_E_B~DUF1744 |
| Common GO terms | GO:0003677 - DNA binding GO:0003887 - DNA-directed DNA polymerase activity GO:0005654 - nucleoplasm GO:0006260 - DNA replication GO:0006261 - DNA-templated DNA replication and 1 others more... |
| Homologous interactions | 4 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
