Interactor 1: DPOE2 (P56282)
DNA polymerase epsilon subunit 2 (DNA polymerase II subunit 2) (DNA polymerase epsilon subunit B)
Gene: POLE2

Interactor 2: DPOE4 (Q9NR33)
DNA polymerase epsilon subunit 4 (DNA polymerase II subunit 4) (DNA polymerase epsilon subunit p12)
Gene: POLE4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.76 0.60 0.678

The method score is based on:

Property Details
Experiments 33961781, 28514442, 10801849
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003677 - DNA binding
GO:0003887 - DNA-directed DNA polymerase activity
GO:0005654 - nucleoplasm
GO:0006261 - DNA-templated DNA replication
GO:0008622 - epsilon DNA polymerase complex
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 527
Hs

1 117
+ Sp
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024