HitPredict

Interactor 1: DPOE2 (P56282)
DNA polymerase epsilon subunit 2 (DNA polymerase II subunit 2) (DNA polymerase epsilon subunit B)
Gene: POLE2

Interactor 2: DPOE3 (Q9NRF9)
DNA polymerase epsilon subunit 3 (Arsenic-transactivated protein) (AsTP) (Chromatin accessibility complex 17 kDa protein) (CHRAC-17) (HuCHRAC17) (DNA polymerase II subunit 3) (DNA polymerase epsilon subunit p17)
Gene: POLE3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.79 0.60 0.689

The method score is based on:

Property Details
Experiments 33961781, 10801849, 28514442
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003887 - DNA-directed DNA polymerase activity
GO:0005654 - nucleoplasm
GO:0006260 - DNA replication
GO:0006261 - DNA-templated DNA replication
GO:0008622 - epsilon DNA polymerase complex
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 527
Hs

1 147
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024