HitPredict

Interactor 1: AP1S2 (P56377)
AP-1 complex subunit sigma-2 (Adaptor protein complex AP-1 subunit sigma-1B) (Adaptor-related protein complex 1 subunit sigma-1B) (Clathrin assembly protein complex 1 sigma-1B small chain) (Golgi adaptor HA1/AP1 adaptin sigma-1B subunit) (Sigma 1B subunit of AP-1 clathrin) (Sigma-adaptin 1B) (Sigma1B-adaptin)
Gene: AP1S2

Interactor 2: EPN4 (Q14677)
Clathrin interactor 1 (Clathrin-interacting protein localized in the trans-Golgi region) (Clint) (Enthoprotin) (Epsin-4) (Epsin-related protein) (EpsinR)
Gene: CLINT1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.675

Property	Details
Experiments	26496610, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005794 - Golgi apparatus GO:0005829 - cytosol GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 157 Hs			1 625
+	Hs
		1057080 AP2M1_HUMAN (1-153): 7.95e-41: 143: 16.23		EPN4_HUMAN (1-625): 2.12e-141: 426: 100.00
+	Rn
		291391 AP2M1_RAT (1-153): 7.95e-41: 143: 16.23		EPN1_RAT (8-529): 1.01e-68: 235: 24.63
+	Hs
		1287553 AP2M1_HUMAN (1-153): 7.95e-41: 143: 16.23		EPN1_HUMAN (8-529): 2.46e-67: 231: 23.55
+	Hs
		203244 AP2M1_HUMAN (1-153): 7.95e-41: 143: 16.23		SYNJ1_HUMAN (120-617): 7.92e-35: 143: 10.29