HitPredict

Interactor 1: UBP5 (P56399)
Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.4.19.12) (Deubiquitinating enzyme 5) (Isopeptidase T) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5)
Gene: Usp5

Interactor 2: ISG15 (Q64339)
Ubiquitin-like protein ISG15 (Interferon-induced 15 kDa protein) (Interferon-induced 17 kDa protein) (IP17) (Ubiquitin cross-reactive protein)
Gene: ISG15

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	14673145
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UBA~ubiquitin, UCH~ubiquitin, ubiquitin~zf-UBP
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 858 Mm			1 161
+	Hs
		474951 UBP5_HUMAN (1-858): 0: 815: 98.37		UBB_HUMAN (2-155): 4.43e-64: 197: 33.12
+	Hs
		475461 UBP5_HUMAN (1-858): 0: 815: 98.37		UBC_HUMAN (2-155): 2.45e-59: 197: 33.12
+	Hs
		800571 UBP5_HUMAN (1-858): 0: 815: 98.37		RS27A_HUMAN (3-78): 2.48e-38: 129: 34.21
+	Rn
		88803 D3ZVQ0_RAT (1-858): 0: 822: 99.18		UBC_RAT (2-108): 8.56e-32: 121: 29.91
+	Mm
		476724 UBP5_MOUSE (1-858): 0: 821: 100.00		UBC_MOUSE (2-108): 5.91e-32: 121: 29.91
+	Hs
		476145 UBP13_HUMAN (2-858): 0: 701: 60.16		UBC_HUMAN (2-155): 2.45e-59: 197: 33.12
+	Hs
		397832 UBP5_HUMAN (1-858): 0: 815: 98.37		ISG15_HUMAN (3-82): 3.14e-09: 54.5: 26.25
+	Mm
		476806 UBP13_MOUSE (2-858): 0: 705: 60.02		UBC_MOUSE (2-108): 5.91e-32: 121: 29.91
+	Rn
		88579 D3ZDI9_RAT (2-858): 0: 695: 59.91		UBC_RAT (2-108): 8.56e-32: 121: 29.91
+	At
		1091780 UBP14_ARATH (7-856): 0: 590: 46.45		UBQ3_ARATH (2-80): 7.88e-26: 101: 31.65
+	Sc
		477245 UBP14_YEAST (11-856): 1.09e-121: 388: 26.85		UBI4P_YEAST (2-79): 1.15e-24: 99.6: 33.33
+	Hs
		259261 UBP12_HUMAN (325-663): 1.3e-72: 244: 18.08		UBC_HUMAN (2-155): 2.45e-59: 197: 33.12
+	Hs
		476213 UBP47_HUMAN (324-680): 8.61e-58: 217: 20.77		UBC_HUMAN (2-155): 2.45e-59: 197: 33.12
+	At
		1092066 UBP12_ARATH (235-752): 2.87e-81: 285: 14.47		UBQ3_ARATH (2-80): 7.88e-26: 101: 31.65
+	At
		1091741 UBP13_ARATH (237-752): 2.42e-78: 277: 13.44		UBQ3_ARATH (2-80): 7.88e-26: 101: 31.65
+	Hs
		476097 UBP33_HUMAN (448-695): 1.97e-46: 181: 14.60		UBC_HUMAN (2-155): 2.45e-59: 197: 33.12
+	Mm
		476865 UBP8_MOUSE (270-651): 2.03e-67: 245: 18.88		UBC_MOUSE (2-108): 5.91e-32: 121: 29.91
+	Rn
		1137288 UBP2_RAT (297-660): 2.02e-67: 237: 14.75		UBC_RAT (2-108): 8.56e-32: 121: 29.91
+	Dm
		1099208 UBPE_DROME (324-613): 4.94e-45: 178: 22.56		R9PY16_DROME (3-156): 8.97e-56: 178: 29.22
+	Mm
		476893 UBP47_MOUSE (290-672): 2.99e-58: 218: 19.90		UBC_MOUSE (2-108): 5.91e-32: 121: 29.91