Interactor 1: IRF5 (P56477)
Interferon regulatory factor 5 (IRF-5)
Gene: IRF5

Interactor 2: IRAK1 (Q62406)
Interleukin-1 receptor-associated kinase 1 (IRAK) (IRAK-1) (EC 2.7.11.1) (Pelle-like protein kinase) (mPLK)
Gene: IRAK1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 0.60 0.584

The method score is based on:

Property Details
Experiments 18824541, 24706909
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0019221 - cytokine-mediated signaling pathway
GO:0032494 - response to peptidoglycan
GO:0045087 - innate immune response
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 497
Mm

1 710
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024