HitPredict

Interactor 1: HDAC1 (P56517)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Interactor 2: HIRA (P79987)
Protein HIRA (cHIRA) (TUP1-like enhancer of split protein 1)
Gene: HIRA

Species: Gallus gallus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	14652010, 15527972
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 480 Gg			1 1019
+	Gg
		880643 HDAC2_CHICK (1-476): 0: 640: 86.13		HIRA_CHICK (1-1019): 0: 802: 100.00
+	Hs
		1024575 HDAC2_HUMAN (1-476): 0: 657: 87.58		CAF1B_HUMAN (1-522): 3.05e-81: 276: 23.23
+	Hs
		1038686 HDAC1_HUMAN (1-445): 0: 657: 95.73		TBL1R_HUMAN (159-407): 2.2e-35: 143: 15.44
+	Hs
		1270423 HDAC2_HUMAN (1-476): 0: 657: 87.58		TBL1R_HUMAN (159-407): 2.2e-35: 143: 15.44
+	Hs
		245600 HDAC1_HUMAN (1-445): 0: 657: 95.73		TBL1X_HUMAN (126-360): 2.04e-30: 129: 21.37
+	Hs
		245623 HDAC2_HUMAN (1-476): 0: 657: 87.58		TBL1X_HUMAN (126-360): 2.04e-30: 129: 21.37
+	Hs
		1270358 HDAC2_HUMAN (1-476): 0: 657: 87.58		FBXW7_HUMAN (253-466): 9.82e-20: 96.8: 12.29
+	Hs
		1270370 HDAC2_HUMAN (1-476): 0: 657: 87.58		SNR40_HUMAN (4-157): 7.3e-13: 73.4: 19.23
+	Hs
		282986 HDAC2_HUMAN (1-476): 0: 657: 87.58		CIAO1_HUMAN (222-367): 1.47e-11: 69.2: 19.33
+	Hs
		903202 HDAC1_HUMAN (1-445): 0: 657: 95.73		WDR5_HUMAN (740-854): 6.74e-11: 66.8: 14.40
+	Hs
		903404 HDAC2_HUMAN (1-476): 0: 657: 87.58		WDR5_HUMAN (740-854): 6.74e-11: 66.8: 14.40
+	Hs
		1017376 HDAC1_HUMAN (1-445): 0: 657: 95.73		CDC20_HUMAN (66-205): 3.07e-10: 65.9: 32.18
+	Hs
		1017414 HDAC2_HUMAN (1-476): 0: 657: 87.58		CDC20_HUMAN (66-205): 3.07e-10: 65.9: 32.18
+	Hs
		177377 HDAC3_HUMAN (9-429): 0: 567: 59.34		TBL1R_HUMAN (159-407): 2.2e-35: 143: 15.44
+	Hs
		177148 HDAC3_HUMAN (9-429): 0: 567: 59.34		TBL1X_HUMAN (126-360): 2.04e-30: 129: 21.37
+	Hs
		177369 HDAC3_HUMAN (9-429): 0: 567: 59.34		TBL1Y_HUMAN (159-360): 7.83e-23: 105: 17.52
+	Dm
		1182201 Q7KTS4_DROME (7-429): 0: 562: 56.85		EBI_DROME (213-374): 3.95e-17: 88.4: 17.71
+	Dm
		1279322 Q9VNC2_DROME (7-429): 0: 558: 56.61		EBI_DROME (213-374): 3.95e-17: 88.4: 17.71
+	Hs
		177249 HDAC3_HUMAN (9-429): 0: 567: 59.34		WDR5_HUMAN (740-854): 6.74e-11: 66.8: 14.40
+	Hs
		245584 HDAC4_HUMAN (11-397): 4.39e-138: 425: 23.63		TBL1X_HUMAN (126-360): 2.04e-30: 129: 21.37