HitPredict

Interactor 1: HDAC4 (P56524)
Histone deacetylase 4 (HD4) (EC 3.5.1.98)
Gene: HDAC4

Interactor 2: GBB1 (P62873)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (Transducin beta chain 1)
Gene: GNB1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	31040226, 16221676
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1084 Hs			1 340
+	Hs
		921778 HDAC5_HUMAN (1-1084): 0: 785: 55.67		GBB2_HUMAN (1-340): 1e-105: 314: 90.29
+	Hs
		921083 HDAC5_HUMAN (1-1084): 0: 785: 55.67		GBB1_HUMAN (1-340): 7.02e-105: 312: 100.00
+	Hs
		903610 HDAC5_HUMAN (1-1084): 0: 785: 55.67		WDR5_HUMAN (4-211): 4.16e-56: 187: 20.93
+	Hs
		1270370 HDAC2_HUMAN (647-1082): 7.5e-161: 486: 20.97		SNR40_HUMAN (130-340): 2.9e-59: 196: 24.30
+	Hs
		921762 HDAC6_HUMAN (574-1040): 2.26e-108: 368: 32.62		GBB2_HUMAN (1-340): 1e-105: 314: 90.29
+	Hs
		1334921 HDAC6_HUMAN (574-1040): 2.26e-108: 368: 32.62		GBB4_HUMAN (1-340): 6.23e-105: 312: 90.88
+	Hs
		921074 HDAC6_HUMAN (574-1040): 2.26e-108: 368: 32.62		GBB1_HUMAN (1-340): 7.02e-105: 312: 100.00
+	Hs
		903202 HDAC1_HUMAN (646-1080): 2.95e-163: 492: 21.68		WDR5_HUMAN (4-211): 4.16e-56: 187: 20.93
+	Hs
		903404 HDAC2_HUMAN (647-1082): 7.5e-161: 486: 20.97		WDR5_HUMAN (4-211): 4.16e-56: 187: 20.93
+	Hs
		177249 HDAC3_HUMAN (651-1083): 8.19e-150: 455: 20.62		WDR5_HUMAN (4-211): 4.16e-56: 187: 20.93