Interactor 1: HDAC4 (P56524)
Histone deacetylase 4 (HD4) (EC 3.5.1.98)
Gene: HDAC4
Interactor 2: MEF2C (Q06413)
Myocyte-specific enhancer factor 2C (Myocyte enhancer factor 2C)
Gene: MEF2C
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 0.60 | 0.756 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 10523670, 32296183, 31040226, 15964851, 18332106, 11486037, 12709441, 15743821, 11279209, unassigned1304, 23752268 |
| Identification Methods | affinity chromatography technology, two hybrid, pull down, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm and 9 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
