HitPredict

Interactor 1: HDAC4 (P56524)
Histone deacetylase 4 (HD4) (EC 3.5.1.98)
Gene: HDAC4

Interactor 2: IKZF2 (Q9UKS7)
Zinc finger protein Helios (Ikaros family zinc finger protein 2)
Gene: IKZF2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	12943985
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1084 Hs			1 526
+	Hs
		1356565 HDAC5_HUMAN (1-1084): 0: 785: 55.67		IKZF2_HUMAN (1-526): 0: 696: 100.00
+	Hs
		880822 HDAC4_HUMAN (1-1072): 0: 974: 100.00		IKZF4_HUMAN (9-524): 3.72e-165: 482: 54.22
+	Hs
		880715 HDAC4_HUMAN (1-1072): 0: 974: 100.00		IKZF1_HUMAN (31-526): 2.39e-164: 478: 54.20
+	Hs
		880849 HDAC4_HUMAN (1-1072): 0: 974: 100.00		IKZF3_HUMAN (10-524): 5.02e-160: 466: 46.52
+	Hs
		1329659 HDAC5_HUMAN (1-1084): 0: 785: 55.67		IKZF4_HUMAN (9-524): 3.72e-165: 482: 54.22
+	Hs
		1033762 HDAC5_HUMAN (1-1084): 0: 785: 55.67		IKZF1_HUMAN (31-526): 2.39e-164: 478: 54.20
+	Hs
		1356578 HDAC5_HUMAN (1-1084): 0: 785: 55.67		IKZF3_HUMAN (10-524): 5.02e-160: 466: 46.52
+	Hs
		1038804 HDAC1_HUMAN (646-1080): 2.95e-163: 492: 21.68		IKZF2_HUMAN (1-526): 0: 696: 100.00
+	Hs
		1270517 HDAC2_HUMAN (647-1082): 7.5e-161: 486: 20.97		IKZF2_HUMAN (1-526): 0: 696: 100.00
+	Hs
		1260190 HDAC7_HUMAN (57-1084): 0: 679: 46.36		IKZF4_HUMAN (9-524): 3.72e-165: 482: 54.22
+	Hs
		1033686 HDAC7_HUMAN (57-1084): 0: 679: 46.36		IKZF1_HUMAN (31-526): 2.39e-164: 478: 54.20
+	Hs
		1260200 HDAC7_HUMAN (57-1084): 0: 679: 46.36		IKZF3_HUMAN (10-524): 5.02e-160: 466: 46.52
+	Hs
		1033633 HDAC1_HUMAN (646-1080): 2.95e-163: 492: 21.68		IKZF1_HUMAN (31-526): 2.39e-164: 478: 54.20
+	Hs
		1270436 HDAC2_HUMAN (647-1082): 7.5e-161: 486: 20.97		IKZF4_HUMAN (9-524): 3.72e-165: 482: 54.22
+	Hs
		1033690 HDAC2_HUMAN (647-1082): 7.5e-161: 486: 20.97		IKZF1_HUMAN (31-526): 2.39e-164: 478: 54.20
+	Hs
		1038805 HDAC1_HUMAN (646-1080): 2.95e-163: 492: 21.68		IKZF3_HUMAN (10-524): 5.02e-160: 466: 46.52
+	Hs
		1270518 HDAC2_HUMAN (647-1082): 7.5e-161: 486: 20.97		IKZF3_HUMAN (10-524): 5.02e-160: 466: 46.52
+	Mm
		140300 HDAC1_MOUSE (646-1080): 3.14e-163: 492: 21.46		Q8C5P6_MOUSE (31-227): 4.19e-78: 248: 66.50
+	Mm
		936415 HDAC2_MOUSE (647-1082): 2.51e-160: 485: 20.97		Q8C5P6_MOUSE (31-227): 4.19e-78: 248: 66.50
+	Hs
		1038742 HDAC1_HUMAN (646-1080): 2.95e-163: 492: 21.68		PRDM5_HUMAN (114-219): 9.82e-10: 63.2: 29.25