HitPredict

Interactor 1: CTBP2 (P56545)
C-terminal-binding protein 2 (CtBP2)
Gene: CTBP2

Interactor 2: CTBP1 (Q13363)
C-terminal-binding protein 1 (CtBP1) (EC 1.1.1.-)
Gene: CTBP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.989

The method score is based on:

Property Details
Experiments 27107012, 30585266, 9858600, 35271311, 25228645, 36414381, 25416956, 26186194, 26496610, 28514442, 33961781, 36688959, 35016035, 36652389, 21988832, 24722188, 31515488, unassigned3473, 31041561
Identification Methods two hybrid, affinity chromatography technology, proximity labelling technology, cross-linking study, validated two hybrid, barcode fusion genetics two hybrid, two hybrid array, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, two hybrid prey pooling approach
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains 2-Hacid_dh~2-Hacid_dh, 2-Hacid_dh~2-Hacid_dh_C, 2-Hacid_dh_C~2-Hacid_dh_C
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001221 - transcription coregulator binding
GO:0001222 - transcription corepressor binding
GO:0003713 - transcription coactivator activity
GO:0003714 - transcription corepressor activity
and 10 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 445
Hs

1 440
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Dm
+ At
+ Sc
+ Sc
+ Sc
+ Cj
+ Ec
+ At
+ Ec
+ Hp
+ Sp

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Last updated: 15 Jul 2024