Interactor 1: CTBP2 (P56545)
C-terminal-binding protein 2 (CtBP2)
Gene: CTBP2

Interactor 2: SOX13 (Q9UN79)
Transcription factor SOX-13 (Islet cell antigen 12) (SRY (Sex determining region Y)-box 13) (Type 1 diabetes autoantigen ICA12)
Gene: SOX13

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.86 0.60 0.722

The method score is based on:

Property Details
Experiments 32296183, 33961781, 30585266, 21988832, unassigned1304
Identification Methods two hybrid, affinity chromatography technology, two hybrid array, validated two hybrid, two hybrid prey pooling approach, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 445
Hs

1 622
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Last updated: 15 Jul 2024