HitPredict

Interactor 1: CTBP2 (P56545)
C-terminal-binding protein 2 (CtBP2)
Gene: CTBP2

Interactor 2: DYR1B (Q9Y463)
Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1) (Minibrain-related kinase) (Mirk protein kinase)
Gene: DYRK1B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	32707033, 23602568
Identification Methods	affinity chromatography technology, pull down, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003713 - transcription coactivator activity GO:0005634 - nucleus
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 445 Hs			1 629
+	Hs
		1032708 CTBP1_HUMAN (20-445): 0: 520: 80.99		DYR1B_HUMAN (1-629): 2.33e-171: 503: 100.00
+	Hs
		647854 CTBP2_HUMAN (1-445): 0: 604: 100.00		MARK3_HUMAN (57-629): 1.59e-123: 384: 18.49
+	Hs
		1032395 CTBP1_HUMAN (20-445): 0: 520: 80.99		DYR1A_HUMAN (19-594): 3.53e-135: 415: 63.57
+	Hs
		681826 CTBP1_HUMAN (20-445): 0: 520: 80.99		AKT1_HUMAN (6-429): 7.87e-119: 363: 18.41
+	Mm
		292437 CTBP2_MOUSE (1-445): 0: 603: 99.55		HIPK1_MOUSE (111-430): 1.53e-54: 202: 37.31
+	Hs
		881285 CTBP2_HUMAN (1-445): 0: 604: 100.00		HIPK2_HUMAN (111-434): 3.93e-52: 196: 36.31
+	Mm
		881370 CTBP2_MOUSE (1-445): 0: 603: 99.55		HIPK2_MOUSE (111-434): 9.48e-52: 194: 36.01
+	Hs
		197300 SERA_HUMAN (35-410): 8.39e-125: 374: 27.32		DYR1A_HUMAN (19-594): 3.53e-135: 415: 63.57
+	Hs
		197229 SERA_HUMAN (35-410): 8.39e-125: 374: 27.32		CDK2_HUMAN (108-376): 5.32e-119: 357: 27.82
+	Hs
		1032606 CTBP1_HUMAN (20-445): 0: 520: 80.99		HIPK2_HUMAN (111-434): 3.93e-52: 196: 36.31
+	At
		188691 CTBP_ARATH (31-351): 2.47e-88: 283: 28.23		KSG7_ARATH (111-475): 9.76e-115: 349: 27.11