HitPredict

Interactor 1: UBE2C (P56616)
Ubiquitin-conjugating enzyme E2 C (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme C) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme C) (UBC-X) (Ubiquitin carrier protein C) (Ubiquitin-protein ligase C)
Gene: UBE2C

Interactor 2: Q5M7C0 (Q5M7C0)
Anaphase-promoting complex subunit 11
Gene: anapc11.L

Species: Xenopus laevis

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	35149681
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~zf-ANAPC11
Common GO terms	GO:0005680 - anaphase-promoting complex GO:0031145 - anaphase-promoting complex-dependent catabolic process GO:0051301 - cell division
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 179 Xl			1 84
+	Sc
		549847 UBC4_YEAST (30-174): 1.29e-76: 227: 36.30		APC11_YEAST (1-84): 8.15e-31: 107: 40.20
+	Hs
		921482 UB2D4_HUMAN (31-175): 5.61e-79: 233: 38.36		RBX1_HUMAN (2-84): 9.29e-29: 100: 39.77
+	Hs
		849303 UB2D1_HUMAN (31-175): 1.7e-78: 232: 38.36		RBX1_HUMAN (2-84): 9.29e-29: 100: 39.77
+	Mm
		895979 UB2D1_MOUSE (31-175): 1.7e-78: 232: 38.36		RBX1_MOUSE (2-84): 9.29e-29: 100: 39.77
+	Hs
		849463 UB2D1_HUMAN (31-175): 1.7e-78: 232: 38.36		APC11_HUMAN (1-84): 9.5e-29: 99.8: 88.10
+	Hs
		919703 UB2D2_HUMAN (31-175): 6.68e-78: 230: 36.30		RBX1_HUMAN (2-84): 9.29e-29: 100: 39.77
+	Mm
		919923 UB2D2_MOUSE (31-175): 6.68e-78: 230: 36.30		RBX1_MOUSE (2-84): 9.29e-29: 100: 39.77
+	Hs
		919882 UB2D2_HUMAN (31-175): 6.68e-78: 230: 36.30		APC11_HUMAN (1-84): 9.5e-29: 99.8: 88.10
+	Ce
		715111 UBC2_CAEEL (31-175): 2.16e-77: 229: 37.67		RBX1_CAEEL (2-84): 3.9e-28: 99: 39.77
+	Hs
		895771 UB2D3_HUMAN (31-175): 2.22e-76: 226: 36.30		RBX1_HUMAN (2-84): 9.29e-29: 100: 39.77
+	Mm
		895973 UB2D3_MOUSE (31-175): 2.22e-76: 226: 36.30		RBX1_MOUSE (2-84): 9.29e-29: 100: 39.77
+	Hs
		895932 UB2D3_HUMAN (31-175): 2.22e-76: 226: 36.30		APC11_HUMAN (1-84): 9.5e-29: 99.8: 88.10
+	Ce
		715108 UBC2_CAEEL (31-175): 2.16e-77: 229: 37.67		APC11_CAEEL (1-84): 1.28e-26: 95.9: 47.13
+	Sc
		549843 UBC4_YEAST (30-174): 1.29e-76: 227: 36.30		RBX1_YEAST (2-84): 8.28e-26: 93.6: 35.23
+	Hs
		1354003 UB2D4_HUMAN (31-175): 5.61e-79: 233: 38.36		RBX2_HUMAN (3-84): 1.18e-22: 85.5: 36.91
+	Hs
		849472 UB2D1_HUMAN (31-175): 1.7e-78: 232: 38.36		RBX2_HUMAN (3-84): 1.18e-22: 85.5: 36.91
+	Hs
		919890 UB2D2_HUMAN (31-175): 6.68e-78: 230: 36.30		RBX2_HUMAN (3-84): 1.18e-22: 85.5: 36.91
+	Hs
		895936 UB2D3_HUMAN (31-175): 2.22e-76: 226: 36.30		RBX2_HUMAN (3-84): 1.18e-22: 85.5: 36.91
+	Hs
		296887 UB2D1_HUMAN (31-175): 1.7e-78: 232: 38.36		LTN1_HUMAN (10-80): 2.09e-18: 79.4: 26.32
+	Hs
		296893 UB2D2_HUMAN (31-175): 6.68e-78: 230: 36.30		LTN1_HUMAN (10-80): 2.09e-18: 79.4: 26.32