HitPredict

Interactor 1: SOX10 (P56693)
Transcription factor SOX-10
Gene: SOX10

Interactor 2: PAXI1 (Q6ZW49)
PAX-interacting protein 1 (PAX transactivation activation domain-interacting protein)
Gene: PAXIP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 466 Hs			1 1069
+	Hs
		1173211 CIC_HUMAN (34-358): 1.95e-43: 166: 19.10		PAXI1_HUMAN (1-419): 4.99e-91: 316: 100.00
+	Hs
		1173227 SOX7_HUMAN (84-451): 9.46e-42: 154: 26.12		PAXI1_HUMAN (1-419): 4.99e-91: 316: 100.00
+	Hs
		303582 SOX30_HUMAN (67-441): 8.76e-40: 154: 21.75		PAXI1_HUMAN (1-419): 4.99e-91: 316: 100.00
+	Hs
		818814 SOX9_HUMAN (13-466): 9.14e-38: 146: 47.14		PAXI1_HUMAN (1-419): 4.99e-91: 316: 100.00
+	Hs
		1173240 SOX17_HUMAN (67-337): 3.55e-38: 145: 27.31		PAXI1_HUMAN (1-419): 4.99e-91: 316: 100.00
+	Hs
		225751 SOX15_HUMAN (102-263): 1.84e-35: 133: 38.32		PAXI1_HUMAN (1-419): 4.99e-91: 316: 100.00
+	Hs
		881831 SOX10_HUMAN (1-466): 2.37e-71: 235: 100.00		CHD7_HUMAN (188-893): 7.26e-34: 144: 9.07
+	Hs
		996901 SSRP1_HUMAN (33-256): 1.02e-29: 124: 17.01		ECT2_HUMAN (26-280): 1.93e-51: 198: 13.97
+	Hs
		1300971 CIC_HUMAN (34-358): 1.95e-43: 166: 19.10		CHD7_HUMAN (188-893): 7.26e-34: 144: 9.07
+	Hs
		1311936 SOX7_HUMAN (84-451): 9.46e-42: 154: 26.12		CHD7_HUMAN (188-893): 7.26e-34: 144: 9.07
+	Hs
		727814 SOX5_HUMAN (96-180): 2.91e-37: 147: 47.06		CHD7_HUMAN (188-893): 7.26e-34: 144: 9.07
+	Hs
		818841 SOX9_HUMAN (13-466): 9.14e-38: 146: 47.14		CHD7_HUMAN (188-893): 7.26e-34: 144: 9.07
+	Hs
		1332326 SOX17_HUMAN (67-337): 3.55e-38: 145: 27.31		CHD7_HUMAN (188-893): 7.26e-34: 144: 9.07
+	Hs
		1199209 PB1_HUMAN (1-338): 2.72e-32: 133: 12.72		CHD7_HUMAN (188-893): 7.26e-34: 144: 9.07
+	Hs
		727934 SOX6_HUMAN (3-301): 1.33e-31: 130: 22.77		CHD7_HUMAN (188-893): 7.26e-34: 144: 9.07
+	Hs
		867119 CIC_HUMAN (34-358): 1.95e-43: 166: 19.10		SC24C_HUMAN (182-460): 3.09e-12: 73.2: 8.84
+	Hs
		300546 CIC_HUMAN (34-358): 1.95e-43: 166: 19.10		NFAT5_HUMAN (180-600): 4.53e-12: 72.7: 15.29
+	Hs
		1243837 SOX7_HUMAN (84-451): 9.46e-42: 154: 26.12		KMT2C_HUMAN (162-612): 3.03e-12: 73.5: 9.11
+	Hs
		818819 SOX9_HUMAN (13-466): 9.14e-38: 146: 47.14		KMT2C_HUMAN (162-612): 3.03e-12: 73.5: 9.11
+	Hs
		1243843 SOX17_HUMAN (67-337): 3.55e-38: 145: 27.31		KMT2C_HUMAN (162-612): 3.03e-12: 73.5: 9.11