Interactor 1: BACE1 (P56817)
Beta-secretase 1 (EC 3.4.23.46) (Aspartyl protease 2) (ASP2) (Asp 2) (Beta-site amyloid precursor protein cleaving enzyme 1) (Beta-site APP cleaving enzyme 1) (Memapsin-2) (Membrane-associated aspartic protease 2)
Gene: BACE1

Interactor 2: SORT (Q99523)
Sortilin (100 kDa NT receptor) (Glycoprotein 95) (Gp95) (Neurotensin receptor 3) (NT3) (NTR3)
Gene: SORT1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 21245145
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005764 - lysosome
GO:0005769 - early endosome
GO:0005794 - Golgi apparatus
GO:0005886 - plasma membrane
GO:0009986 - cell surface
and 3 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 501
Hs

1 831
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024