HitPredict

Interactor 1: BCAR1 (P56945)
Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (Cas scaffolding protein family member 1) (p130cas)
Gene: BCAR1

Interactor 2: GGYF2 (Q6Y7W6)
GRB10-interacting GYF protein 2 (PERQ amino acid-rich with GYF domain-containing protein 2) (Trinucleotide repeat-containing gene 15 protein)
Gene: GIGYF2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	28007913
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 870 Hs			1 1299
+	Hs
		876338 BCAR1_HUMAN (1-870): 2.49e-107: 352: 100.00		AFAD_HUMAN (299-880): 8.47e-55: 212: 16.30
+	Hs
		882396 BCAR1_HUMAN (1-870): 2.49e-107: 352: 100.00		KI21A_HUMAN (684-1261): 2.48e-30: 132: 13.71
+	Hs
		728456 BCAR1_HUMAN (1-870): 2.49e-107: 352: 100.00		MYH11_HUMAN (705-1294): 1.67e-26: 120: 9.81
+	Hs
		876363 DYST_HUMAN (457-866): 1.71e-67: 248: 12.07		AFAD_HUMAN (299-880): 8.47e-55: 212: 16.30
+	Hs
		882665 BCAR1_HUMAN (1-870): 2.49e-107: 352: 100.00		MRCKB_HUMAN (731-1123): 2.65e-12: 73.9: 14.82
+	Hs
		724828 CASL_HUMAN (1-868): 1.02e-91: 309: 35.96		MYH9_HUMAN (349-1161): 1.1e-19: 98.3: 10.26
+	Hs
		725073 MACF1_HUMAN (505-867): 1.44e-74: 269: 13.79		MYH9_HUMAN (349-1161): 1.1e-19: 98.3: 10.26
+	Hs
		1068700 MACF1_HUMAN (505-867): 1.44e-74: 269: 13.79		PLEC_HUMAN (324-1292): 6.24e-14: 79.4: 8.88
+	Hs
		724786 DYST_HUMAN (457-866): 1.71e-67: 248: 12.07		MYH9_HUMAN (349-1161): 1.1e-19: 98.3: 10.26
+	Hs
		974083 DYST_HUMAN (457-866): 1.71e-67: 248: 12.07		ITSN1_HUMAN (767-1126): 1.03e-17: 91.7: 16.62
+	Mm
		222888 ACK1_MOUSE (9-581): 1.34e-29: 128: 13.93		AFAD_MOUSE (299-881): 3.09e-54: 210: 16.18
+	Hs
		876420 DNMBP_HUMAN (7-559): 6.75e-29: 126: 15.27		AFAD_HUMAN (299-880): 8.47e-55: 212: 16.30
+	Hs
		297818 K0754_HUMAN (151-869): 1.64e-27: 122: 10.56		AFAD_HUMAN (299-880): 8.47e-55: 212: 16.30
+	Hs
		110636 H3BPE1_HUMAN (480-867): 1.8e-35: 148: 13.10		MYH9_HUMAN (349-1161): 1.1e-19: 98.3: 10.26
+	Dm
		1370328 Q9VLS7_DROME (65-706): 2.75e-10: 66.5: 9.08		Q9VXE3_DROME (601-1255): 1.33e-34: 146: 13.43
+	Mm
		222875 ACK1_MOUSE (9-581): 1.34e-29: 128: 13.93		MYH9_MOUSE (927-1298): 3.12e-14: 80.1: 7.51
+	Hs
		297971 FCSD2_HUMAN (3-156): 3.32e-24: 110: 24.68		ITSN1_HUMAN (767-1126): 1.03e-17: 91.7: 16.62
+	Mm
		222845 ACK1_MOUSE (9-581): 1.34e-29: 128: 13.93		MYH10_MOUSE (739-1030): 1.45e-09: 65: 16.72
+	Hs
		1078886 SH3K1_HUMAN (7-294): 1.08e-16: 86.7: 16.44		ITSN1_HUMAN (767-1126): 1.03e-17: 91.7: 16.62
+	Dm
		1370358 Q9VLS7_DROME (65-706): 2.75e-10: 66.5: 9.08		Q9W179_DROME (739-1025): 9.57e-14: 78.5: 19.47