HitPredict

Interactor 1: BCAR1 (P56945)
Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (Cas scaffolding protein family member 1) (p130cas)
Gene: BCAR1

Interactor 2: ANS1A (Q92625)
Ankyrin repeat and SAM domain-containing protein 1A (Odin)
Gene: ANKS1A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	32296183
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Ank_2~SH3_1
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 870 Hs			1 1134
+	Hs
		1054786 CASL_HUMAN (1-868): 1.02e-91: 309: 35.96		ANS1A_HUMAN (1-1134): 0: 792: 100.00
+	Hs
		1268507 CASS4_HUMAN (4-865): 6.37e-38: 154: 19.91		ANS1A_HUMAN (1-1134): 0: 792: 100.00
+	Hs
		297990 FCSD2_HUMAN (3-156): 3.32e-24: 110: 24.68		ANS1A_HUMAN (1-1134): 0: 792: 100.00
+	Hs
		1268487 SH3K1_HUMAN (7-294): 1.08e-16: 86.7: 16.44		ANS1A_HUMAN (1-1134): 0: 792: 100.00
+	Hs
		1191811 CASS4_HUMAN (4-865): 6.37e-38: 154: 19.91		ANS1B_HUMAN (1-1101): 0: 593: 33.52
+	Hs
		882339 BCAR1_HUMAN (1-870): 2.49e-107: 352: 100.00		Q49AR9_HUMAN (675-1134): 2.78e-116: 374: 92.70
+	Hs
		1054772 CASL_HUMAN (1-868): 1.02e-91: 309: 35.96		Q49AR9_HUMAN (675-1134): 2.78e-116: 374: 92.70
+	Hs
		297974 FCSD2_HUMAN (3-156): 3.32e-24: 110: 24.68		Q49AR9_HUMAN (675-1134): 2.78e-116: 374: 92.70
+	Hs
		1115812 SH3K1_HUMAN (7-294): 1.08e-16: 86.7: 16.44		Q49AR9_HUMAN (675-1134): 2.78e-116: 374: 92.70
+	Hs
		965174 MACF1_HUMAN (505-867): 1.44e-74: 269: 13.79		ANK2_HUMAN (180-837): 1.86e-34: 146: 13.55
+	Hs
		1330882 MACF1_HUMAN (505-867): 1.44e-74: 269: 13.79		Q9H4D1_HUMAN (60-245): 4.58e-19: 95.1: 38.17
+	Hs
		883671 MACF1_HUMAN (505-867): 1.44e-74: 269: 13.79		RIPK4_HUMAN (60-245): 1.22e-18: 94: 37.63
+	Dm
		1361443 Q9VLS7_DROME (65-706): 2.75e-10: 66.5: 9.08		Q9VAU5_DROME (24-849): 7.18e-77: 281: 15.02
+	Hs
		1263386 SH3K1_HUMAN (7-294): 1.08e-16: 86.7: 16.44		CSKI2_HUMAN (1-592): 3.95e-69: 255: 24.71
+	Mm
		103609 MICA3_MOUSE (64-629): 8.45e-26: 117: 12.40		ANK3_MOUSE (180-812): 1.06e-40: 166: 12.56
+	Mm
		222869 ACK1_MOUSE (9-581): 1.34e-29: 128: 13.93		ANK2_MOUSE (180-812): 1.69e-33: 143: 13.36
+	Hs
		310053 MDC1_HUMAN (48-774): 9.36e-10: 64.9: 9.16		TNKS1_HUMAN (3-202): 3.44e-41: 167: 30.99
+	Dm
		1362722 Q9VLS7_DROME (65-706): 2.75e-10: 66.5: 9.08		ANKHM_DROME (1-171): 1.47e-27: 123: 26.16
+	Dm
		1182373 Q9VLS7_DROME (65-706): 2.75e-10: 66.5: 9.08		Q7KU92_DROME (243-419): 1.36e-18: 94.4: 14.69
+	Hs
		1056981 MDC1_HUMAN (48-774): 9.36e-10: 64.9: 9.16		TNKS2_HUMAN (289-680): 1.09e-12: 74.8: 9.90