HitPredict

Interactor 1: FUS (P56959)
RNA-binding protein FUS (Protein pigpen)
Gene: FUS

Interactor 2: CUL3 (Q9JLV5)
Cullin-3 (CUL-3)
Gene: CUL3

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	23086144
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0006357 - regulation of transcription by RNA polymerase II GO:0010467 - gene expression
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 518 Mm			1 768
+	Hs
		1042197 RBP56_HUMAN (3-447): 8.79e-40: 154: 45.41		CUL3_HUMAN (1-768): 0: 952: 99.48
+	Hs
		212139 HTSF1_HUMAN (150-365): 6.61e-39: 153: 13.43		CUL3_HUMAN (1-768): 0: 952: 99.48
+	Hs
		726803 FUS_HUMAN (1-518): 1.02e-35: 141: 84.82		CUL3_HUMAN (1-768): 0: 952: 99.48
+	Hs
		123934 SPT5H_HUMAN (15-228): 1.41e-31: 131: 15.81		CUL3_HUMAN (1-768): 0: 952: 99.48
+	Hs
		967158 EWS_HUMAN (3-444): 5.23e-30: 126: 34.13		CUL3_HUMAN (1-768): 0: 952: 99.48
+	Hs
		1043138 RBP56_HUMAN (3-447): 8.79e-40: 154: 45.41		CUL4A_HUMAN (10-768): 0: 801: 38.45
+	Hs
		1043490 RBP56_HUMAN (3-447): 8.79e-40: 154: 45.41		CUL4B_HUMAN (5-768): 0: 795: 36.77
+	Hs
		726804 FUS_HUMAN (1-518): 1.02e-35: 141: 84.82		CUL4A_HUMAN (10-768): 0: 801: 38.45
+	Hs
		726805 FUS_HUMAN (1-518): 1.02e-35: 141: 84.82		CUL4B_HUMAN (5-768): 0: 795: 36.77
+	Hs
		967159 EWS_HUMAN (3-444): 5.23e-30: 126: 34.13		CUL4A_HUMAN (10-768): 0: 801: 38.45
+	Hs
		967160 EWS_HUMAN (3-444): 5.23e-30: 126: 34.13		CUL4B_HUMAN (5-768): 0: 795: 36.77
+	Hs
		1041126 RBP56_HUMAN (3-447): 8.79e-40: 154: 45.41		CUL1_HUMAN (18-768): 0: 707: 29.94
+	Hs
		726801 FUS_HUMAN (1-518): 1.02e-35: 141: 84.82		CUL1_HUMAN (18-768): 0: 707: 29.94
+	Hs
		967156 EWS_HUMAN (3-444): 5.23e-30: 126: 34.13		CUL1_HUMAN (18-768): 0: 707: 29.94
+	Hs
		1041420 RBP56_HUMAN (3-447): 8.79e-40: 154: 45.41		CUL2_HUMAN (30-768): 0: 670: 26.30
+	Hs
		726802 FUS_HUMAN (1-518): 1.02e-35: 141: 84.82		CUL2_HUMAN (30-768): 0: 670: 26.30
+	Hs
		967157 EWS_HUMAN (3-444): 5.23e-30: 126: 34.13		CUL2_HUMAN (30-768): 0: 670: 26.30
+	Hs
		1271154 RBP56_HUMAN (3-447): 8.79e-40: 154: 45.41		CUL5_HUMAN (25-768): 0: 596: 23.77
+	Hs
		726974 FUS_HUMAN (1-518): 1.02e-35: 141: 84.82		CUL5_HUMAN (25-768): 0: 596: 23.77
+	Hs
		967326 EWS_HUMAN (3-444): 5.23e-30: 126: 34.13		CUL5_HUMAN (25-768): 0: 596: 23.77