HitPredict

Interactor 1: DSCR6 (P57055)
Protein ripply3 (Down syndrome critical region protein 6)
Gene: RIPPLY3

Interactor 2: SPB13 (Q9UIV8)
Serpin B13 (HaCaT UV-repressible serpin) (Hurpin) (Headpin) (Peptidase inhibitor 13) (PI-13) (Proteinase inhibitor 13)
Gene: SERPINB13

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 190 Hs			1 391
+	Hs
		820292 DSCR6_HUMAN (1-190): 8.5e-104: 298: 100.00		SPB4_HUMAN (1-391): 1.53e-161: 460: 58.16
+	Hs
		667936 DSCR6_HUMAN (1-190): 8.5e-104: 298: 100.00		SPB3_HUMAN (1-391): 4.96e-159: 454: 57.91
+	Hs
		675631 DSCR6_HUMAN (1-190): 8.5e-104: 298: 100.00		ILEU_HUMAN (1-391): 2.14e-154: 442: 45.46
+	Hs
		839472 DSCR6_HUMAN (1-190): 8.5e-104: 298: 100.00		SPB8_HUMAN (1-391): 1.64e-154: 442: 39.29
+	Hs
		271859 DSCR6_HUMAN (1-190): 8.5e-104: 298: 100.00		SPB7_HUMAN (1-391): 5.52e-144: 415: 37.50
+	Hs
		344182 DSCR6_HUMAN (1-190): 8.5e-104: 298: 100.00		A1AT_HUMAN (2-391): 6.79e-137: 398: 28.90
+	Hs
		738736 DSCR6_HUMAN (1-190): 8.5e-104: 298: 100.00		SPB5_HUMAN (1-391): 1.32e-135: 394: 32.07