HitPredict

Interactor 1: RIPK4 (P57078)
Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain-containing protein 3) (PKC-delta-interacting protein kinase)
Gene: RIPK4

Interactor 2: FKB1A (P62942)
Peptidyl-prolyl cis-trans isomerase FKBP1A (PPIase FKBP1A) (EC 5.2.1.8) (12 kDa FK506-binding protein) (12 kDa FKBP) (FKBP-12) (Calstabin-1) (FK506-binding protein 1A) (FKBP-1A) (Immunophilin FKBP12) (Rotamase)
Gene: FKBP1A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	32707033
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	FKBP_C~Pkinase
Common GO terms	GO:0005737 - cytoplasm GO:0016020 - membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 832 Hs			1 108
+	Hs
		883486 RIPK4_HUMAN (1-832): 0: 726: 100.00		FKBP3_HUMAN (5-108): 5.68e-42: 138: 40.18
+	Hs
		923838 Q9H4D1_HUMAN (1-832): 0: 697: 90.75		FKB1A_HUMAN (1-108): 2e-54: 166: 100.00
+	Hs
		961567 Q9H4D1_HUMAN (1-832): 0: 697: 90.75		FKBP3_HUMAN (5-108): 5.68e-42: 138: 40.18
+	Hs
		883489 RIPK4_HUMAN (1-832): 0: 726: 100.00		FKBP4_HUMAN (2-108): 1.57e-15: 72.4: 27.03
+	Hs
		883504 RIPK4_HUMAN (1-832): 0: 726: 100.00		FKBP5_HUMAN (2-108): 3.73e-15: 71.3: 28.44
+	Hs
		972586 Q9H4D1_HUMAN (1-832): 0: 697: 90.75		FKBP4_HUMAN (2-108): 1.57e-15: 72.4: 27.03
+	Hs
		1034995 Q9H4D1_HUMAN (1-832): 0: 697: 90.75		FKBP5_HUMAN (2-108): 3.73e-15: 71.3: 28.44
+	Hs
		1034933 ANKK1_HUMAN (342-643): 1.15e-46: 180: 19.47		FKBP5_HUMAN (2-108): 3.73e-15: 71.3: 28.44
+	Hs
		972616 RIPK3_HUMAN (21-371): 4.07e-34: 139: 30.39		FKBP4_HUMAN (2-108): 1.57e-15: 72.4: 27.03
+	Hs
		1035071 RIPK3_HUMAN (21-371): 4.07e-34: 139: 30.39		FKBP5_HUMAN (2-108): 3.73e-15: 71.3: 28.44