HitPredict

Interactor 1: RIPK4 (P57078)
Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain-containing protein 3) (PKC-delta-interacting protein kinase)
Gene: RIPK4

Interactor 2: TBA1B (P68363)
Tubulin alpha-1B chain (EC 3.6.5.-) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) (Tubulin alpha-ubiquitous chain) [Cleaved into: Detyrosinated tubulin alpha-1B chain]
Gene: TUBA1B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	26972000
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Ank_2~Tubulin, Ank_4~Tubulin, Ank_4~Tubulin_C
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 832 Hs			1 451
+	Hs
		428113 RIPK4_HUMAN (1-832): 0: 726: 100.00		TBB5_HUMAN (1-439): 0: 699: 41.23
+	Hs
		883476 RIPK4_HUMAN (1-832): 0: 726: 100.00		TBB4B_HUMAN (1-437): 0: 697: 40.96
+	Hs
		933351 Q9H4D1_HUMAN (1-832): 0: 697: 90.75		TBA1B_HUMAN (1-440): 0: 717: 100.00
+	Hs
		428431 Q9H4D1_HUMAN (1-832): 0: 697: 90.75		TBB5_HUMAN (1-439): 0: 699: 41.23
+	Hs
		933974 Q9H4D1_HUMAN (1-832): 0: 697: 90.75		TBB4B_HUMAN (1-437): 0: 697: 40.96
+	Hs
		862023 DAPK1_HUMAN (513-831): 7.19e-83: 292: 25.16		TBB4B_HUMAN (1-437): 0: 697: 40.96
+	Hs
		965128 ANK2_HUMAN (592-832): 1.31e-65: 241: 27.89		TBA1A_HUMAN (1-440): 0: 715: 99.55
+	Hs
		428145 ANK2_HUMAN (592-832): 1.31e-65: 241: 27.89		TBB5_HUMAN (1-439): 0: 699: 41.23
+	Hs
		201743 RIPK2_HUMAN (31-276): 6.59e-54: 197: 44.94		TBB5_HUMAN (1-439): 0: 699: 41.23
+	Hs
		428522 RIPK3_HUMAN (21-371): 4.07e-34: 139: 30.39		TBB5_HUMAN (1-439): 0: 699: 41.23
+	Hs
		428187 RIPK1_HUMAN (19-278): 1.18e-32: 137: 34.31		TBB5_HUMAN (1-439): 0: 699: 41.23