HitPredict

Interactor 1: RIPK4 (P57078)
Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain-containing protein 3) (PKC-delta-interacting protein kinase)
Gene: RIPK4

Interactor 2: TBB4B (P68371)
Tubulin beta-4B chain (Tubulin beta-2 chain) (Tubulin beta-2C chain)
Gene: TUBB4B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	26972000
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Ank_2~Tubulin, Ank_4~Tubulin, Ank_4~Tubulin_C
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 832 Hs			1 445
+	Hs
		883508 RIPK4_HUMAN (1-832): 0: 726: 100.00		TBB3_HUMAN (1-443): 0: 714: 93.23
+	Hs
		428113 RIPK4_HUMAN (1-832): 0: 726: 100.00		TBB5_HUMAN (1-429): 0: 711: 98.37
+	Hs
		883632 RIPK4_HUMAN (1-832): 0: 726: 100.00		TBB2B_HUMAN (1-430): 0: 710: 98.14
+	Hs
		883510 RIPK4_HUMAN (1-832): 0: 726: 100.00		TBB2A_HUMAN (1-430): 0: 707: 97.67
+	Hs
		381154 RIPK4_HUMAN (1-832): 0: 726: 100.00		TBB4A_HUMAN (1-427): 0: 706: 98.60
+	Hs
		883630 RIPK4_HUMAN (1-832): 0: 726: 100.00		TBB6_HUMAN (1-432): 0: 706: 92.36
+	Hs
		1037393 Q9H4D1_HUMAN (1-832): 0: 697: 90.75		TBB3_HUMAN (1-443): 0: 714: 93.23
+	Hs
		428431 Q9H4D1_HUMAN (1-832): 0: 697: 90.75		TBB5_HUMAN (1-429): 0: 711: 98.37
+	Hs
		933974 Q9H4D1_HUMAN (1-832): 0: 697: 90.75		TBB4B_HUMAN (1-427): 0: 711: 100.00
+	Hs
		1313672 Q9H4D1_HUMAN (1-832): 0: 697: 90.75		TBB2B_HUMAN (1-430): 0: 710: 98.14
+	Hs
		1046578 Q9H4D1_HUMAN (1-832): 0: 697: 90.75		TBB2A_HUMAN (1-430): 0: 707: 97.67
+	Hs
		1312810 Q9H4D1_HUMAN (1-832): 0: 697: 90.75		TBB6_HUMAN (1-432): 0: 706: 92.36
+	Hs
		381300 Q9H4D1_HUMAN (1-832): 0: 697: 90.75		TBB4A_HUMAN (1-427): 0: 706: 98.60
+	Hs
		862023 DAPK1_HUMAN (513-831): 7.19e-83: 292: 25.16		TBB4B_HUMAN (1-427): 0: 711: 100.00
+	Hs
		428145 ANK2_HUMAN (592-832): 1.31e-65: 241: 27.89		TBB5_HUMAN (1-429): 0: 711: 98.37
+	Hs
		965103 ANK2_HUMAN (592-832): 1.31e-65: 241: 27.89		TBB2A_HUMAN (1-430): 0: 707: 97.67
+	Hs
		201743 RIPK2_HUMAN (31-276): 6.59e-54: 197: 44.94		TBB5_HUMAN (1-429): 0: 711: 98.37
+	Hs
		201824 RIPK2_HUMAN (31-276): 6.59e-54: 197: 44.94		TBB2B_HUMAN (1-430): 0: 710: 98.14
+	Hs
		201739 RIPK2_HUMAN (31-276): 6.59e-54: 197: 44.94		TBB4A_HUMAN (1-427): 0: 706: 98.60
+	Hs
		381334 RIPK3_HUMAN (21-371): 4.07e-34: 139: 30.39		TBB4A_HUMAN (1-427): 0: 706: 98.60