HitPredict

Interactor 1: RIPK4 (P57078)
Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain-containing protein 3) (PKC-delta-interacting protein kinase)
Gene: RIPK4

Interactor 2: FARP1 (Q9Y4F1)
FERM, ARHGEF and pleckstrin domain-containing protein 1 (Chondrocyte-derived ezrin-like protein) (FERM, RhoGEF and pleckstrin domain-containing protein 1) (Pleckstrin homology domain-containing family C member 2) (PH domain-containing family C member 2)
Gene: FARP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	26972000
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	PH~Pkinase
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 832 Hs			1 1045
+	Hs
		1330900 Q9H4D1_HUMAN (1-832): 0: 697: 90.75		FARP1_HUMAN (1-1045): 0: 848: 100.00
+	Hs
		299252 RIPK4_HUMAN (1-832): 0: 726: 100.00		FARP2_HUMAN (1-1040): 0: 780: 53.19
+	Hs
		299289 Q9H4D1_HUMAN (1-832): 0: 697: 90.75		FARP2_HUMAN (1-1040): 0: 780: 53.19
+	Hs
		883679 RIPK4_HUMAN (1-832): 0: 726: 100.00		E41L3_HUMAN (35-538): 1.5e-115: 384: 30.87
+	Hs
		965179 ANK2_HUMAN (592-832): 1.31e-65: 241: 27.89		FARP1_HUMAN (1-1045): 0: 848: 100.00
+	Hs
		1330892 Q9H4D1_HUMAN (1-832): 0: 697: 90.75		E41L3_HUMAN (35-538): 1.5e-115: 384: 30.87
+	Hs
		1021479 ANK3_HUMAN (659-832): 4.77e-45: 178: 32.57		FARP1_HUMAN (1-1045): 0: 848: 100.00
+	Hs
		640287 ANR50_HUMAN (353-788): 9.53e-101: 343: 24.36		PTN3_HUMAN (21-586): 8.74e-101: 340: 21.22
+	Hs
		965178 ANK2_HUMAN (592-832): 1.31e-65: 241: 27.89		E41L3_HUMAN (35-538): 1.5e-115: 384: 30.87
+	Hs
		547010 ANK2_HUMAN (592-832): 1.31e-65: 241: 27.89		EZRI_HUMAN (37-558): 4.42e-103: 337: 20.07
+	Hs
		640286 KDIS_HUMAN (251-655): 7.94e-53: 202: 18.63		PTN3_HUMAN (21-586): 8.74e-101: 340: 21.22
+	Hs
		547272 KDIS_HUMAN (251-655): 7.94e-53: 202: 18.63		EZRI_HUMAN (37-558): 4.42e-103: 337: 20.07
+	Hs
		201750 RIPK2_HUMAN (31-276): 6.59e-54: 197: 44.94		EZRI_HUMAN (37-558): 4.42e-103: 337: 20.07
+	Hs
		1336475 KDIS_HUMAN (251-655): 7.94e-53: 202: 18.63		E41LA_HUMAN (37-584): 4.2e-99: 329: 23.37
+	Hs
		547029 ANK3_HUMAN (659-832): 4.77e-45: 178: 32.57		EZRI_HUMAN (37-558): 4.42e-103: 337: 20.07
+	Hs
		1021466 ANK3_HUMAN (659-832): 4.77e-45: 178: 32.57		E41LA_HUMAN (37-584): 4.2e-99: 329: 23.37
+	Hs
		257705 ANR17_HUMAN (384-541): 2.36e-20: 99.6: 14.47		E41L5_HUMAN (7-551): 1.15e-122: 394: 26.72
+	Hs
		1219853 ANKH1_HUMAN (384-541): 3.69e-19: 95.3: 14.47		E41L5_HUMAN (7-551): 1.15e-122: 394: 26.72
+	Hs
		166880 ANR28_HUMAN (252-539): 5.33e-14: 78.4: 10.62		EZRI_HUMAN (37-558): 4.42e-103: 337: 20.07